Recently, a growing literature has supported the concept that large nodules usually found in
cirrhotic livers represent premalignant lesions in chronic liver disease. Using advanced …

In recent years, a growing literature has supported the concept that large nodules usually
found in cirrhotic livers represent premalignant lesions in the setting of chronic liver disease …

The number of dysplastic nodules detected clinically has increased since patients with
hepatitis virus-associated cirrhosis, who are at increased risk for hepatocellular carcinoma …

Although increasing numbers of equivocal nodular lesions have been detected in patients
with liver cirrhosis with the development of various diagnostic imaging modalities, the …

BACKGROUND Advances in imaging technology have enhanced the detection of small
nodular lesions during the course of chronic liver disease. METHODS Between 1995 and …

It has been established that small, equivocal nodular lesions such as dysplastic nodules
(DNs) and small well-differentiated hepatocellular carcinomas (early HCCs) are frequently …

In Japan, the presence of a large regenerative nodule within a cirrhotic liver, referred to as a
macroregenerative nodule or adenomatous hyperplasia, is thought to play a role in the …

The multistep process of hepatic carcinogenesis is mirrored by the morphologic
classification of lesions detectable in cirrhosis, which include large regenerative nodules …

The early stages of hepatocarcinogenesis in human chronic liver diseases are characterized
by the emergence of preneoplastic lesions of which some will eventually develop into …

In order to reveal the precursor lesion of hepatocellular carcinoma, a histopathologic study
was performed on 141 cases of liver cirrhosis with or without hepatocellular carcinoma …