Efficient TNBC immunotherapy by dual reprogramming tumor-infiltrating dendritic cells and tumor-associated macrophages with stimulus-responsive miR155 …
Z Jing, Y Li, J Song, X Zang - International Journal of Biological …, 2023 - Elsevier
Triple negative breast cancer (TNBC) remains to be a formidable adversary with high
mortality and unfavorable prognosis. Tumor microenvironment comprises of various …
mortality and unfavorable prognosis. Tumor microenvironment comprises of various …
[PDF][PDF] Uncoupling tumor necrosis factor-α and interleukin-10 at tumor immune microenvironment of breast cancer through miR-17-5p/MALAT-1/H19 circuit
Triple Negative Breast Cancer (TNBC) immunotherapy has recently shown promising
approach. However, some TNBC patients presented with resistance. One of the reasons …
approach. However, some TNBC patients presented with resistance. One of the reasons …
Reactive oxygen species/glutathione dual sensitive nanoparticles with encapsulation of miR155 and curcumin for synergized cancer immunotherapy
K Li, J Wang, Y Xie, Z Lu, W Sun, K Wang… - Journal of …, 2024 - Springer
Considerable attention has been directed towards exploring the potential efficacy of miR-
155 in the realm of cancer immunotherapy. Elevated levels of miR-155 in dendritic cells …
155 in the realm of cancer immunotherapy. Elevated levels of miR-155 in dendritic cells …
Tumor associated macrophage-targeted microRNA delivery with dual-responsive polypeptide nanovectors for anti-cancer therapy
Abstract Repolarizing Tumor-associated macrophages (TAMs) to anti-tumor M1
macrophages with microRNA (miR) is a plausible approach for cancer treatment. However …
macrophages with microRNA (miR) is a plausible approach for cancer treatment. However …
An adjuvant micelle-based multifunctional nanosystem for tumor immunotherapy by remodeling three types of immunosuppressive cells
S Meng, H Du, X Li, X Zheng, P Zhao, Z Yuan… - ACS …, 2024 - ACS Publications
Immunotherapy is restricted by a complex tumor immunosuppressive microenvironment
(TIM) and low drug delivery efficiency. Herein, a multifunctional adjuvant micelle …
(TIM) and low drug delivery efficiency. Herein, a multifunctional adjuvant micelle …
Targeted delivery of miRNA 155 to tumor associated macrophages for tumor immunotherapy
X Zang, X Zhang, X Zhao, H Hu, M Qiao… - Molecular …, 2019 - ACS Publications
Tumor associated macrophages (TAMs) are important components residing in the tumor
microenvironment. They are immunosuppressive and promote tumor progression. Targeting …
microenvironment. They are immunosuppressive and promote tumor progression. Targeting …
Integrated nanovaccine with microRNA-148a inhibition reprograms tumor-associated dendritic cells by modulating miR-148a/DNMT1/SOCS1 axis
Immunosuppressive tumor-associated dendritic cells (TADCs) are potential targets for
cancer therapy. However, their poor responsiveness to TLR stimulation is a major obstacle …
cancer therapy. However, their poor responsiveness to TLR stimulation is a major obstacle …
Development of toll-like receptor agonist-loaded nanoparticles as precision immunotherapy for reprogramming tumor-associated macrophages
Y Zhang, Y Chen, J Li, X Zhu, Y Liu… - … Applied Materials & …, 2021 - ACS Publications
Most cancers contain abundant tumor-associated macrophages (TAMs). TAMs usually
display a tumor-supportive M2-like phenotype; they promote tumor growth and influence …
display a tumor-supportive M2-like phenotype; they promote tumor growth and influence …
Reactive oxygen species‐responsive dual‐targeted nanosystem promoted immunogenic cell death against breast cancer
The development of an optimal treatment modality to improve the therapeutic outcome of
breast cancer patients is still difficult. Poor antigen presentation to T cells is a major …
breast cancer patients is still difficult. Poor antigen presentation to T cells is a major …
A Dual Enhancing Strategy of Novel Nanovaccine Based on TIM3 Silencing Nanoadjuvants and Desialylated Cancer Cell Membrane Antigens for Personalized …
K Li, X Li, J Wu, H Wu, M Wu, Y Zhou… - Advanced Functional …, 2024 - Wiley Online Library
Cancer vaccines represent a promising form of immunotherapy employed in the treatment of
cancer. However, their efficiency in eliciting immune responses is limited, and satisfactory …
cancer. However, their efficiency in eliciting immune responses is limited, and satisfactory …