AM Samuels, D Ansong, SK Kariuki, S Adjei… - The Lancet Infectious …, 2022 - thelancet.com
Background Controlled infection studies in malaria-naive adults suggest increased vaccine efficacy for fractional-dose versus full-dose regimens of RTS, S/AS01. We report first results …
A Olotu, G Fegan, J Wambua… - … England Journal of …, 2016 - Mass Medical Soc
Background The candidate malaria vaccine RTS, S/AS01 is being evaluated in order to inform a decision regarding its inclusion in routine vaccination schedules. Methods We …
A Leach, J Vekemans, M Lievens, O Ofori-Anyinam… - Malaria journal, 2011 - Springer
Abstract Background GlaxoSmithKline Biologicals and the PATH Malaria Vaccine Initiative are working in partnership to develop a malaria vaccine to protect infants and children living …
Background The efficacy of RTS, S/AS01 as a vaccine for malaria is being tested in a phase 3 clinical trial. Early results show significant, albeit partial, protection against clinical malaria …
KP Asante, DP Mathanga, P Milligan, S Akech, A Oduro… - The Lancet, 2024 - thelancet.com
Summary Background The RTS, S/AS01 E malaria vaccine (RTS, S) was introduced by national immunisation programmes in Ghana, Kenya, and Malawi in 2019 in large-scale …
Background The target delivery channel of RTS, S candidate malaria vaccines in malaria- endemic countries in Africa is the World Health Organisation Expanded Program on …
Background A malaria vaccine could be an important addition to current control strategies. We report the safety and vaccine efficacy (VE) of the RTS, S/AS01 vaccine during 18 mo …
E Macete, JJ Aponte, C Guinovart… - Tropical Medicine & …, 2007 - Wiley Online Library
Background The development of a malaria vaccine remains a public health priority for sub‐ Saharan Africa. RTS, S/AS02A candidate malaria vaccine has been shown to be safe and …
The malaria vaccine candidate, RTS, S/AS01E, showed promising protective efficacy in a trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the …