Einleitung: Trotz Behandlung mit direkten oralen Antikoagulanzien (DOAK) besteht bei
Patienten mit Vorhofflimmern ein jährliches Schlaganfallrisiko von 1-2%. Zusätzlich …

Background and Purpose Accurate and rapid assessment of coagulation status is necessary
to guide thrombolysis or reversal of anticoagulation in stroke patients, but commercially …

Introduction: Non-vitamin K antagonist oral anticoagulants (NOAC) are increasingly
replacing vitamin K antagonists for prevention of thromboembolism in atrial fibrillation (AF) …

Randomized trials suggest superior and safe stroke prevention in patients with atrial
fibrillation after anticoagulation with dabigatran (D) at a 150 mg BID as described in the RE …

Background Direct oral anticoagulants (DOAC) including edoxaban are increasingly used
for stroke prevention in atrial fibrillation. Despite treatment, annual stroke rate in these …

To describe the effect of dabigatran on thrombin time (TT) reagents at different
concentrations of thrombin. Pooled normal plasma enriched with dabigatran was dissolved …

Introduction The oral direct thrombin inhibitor dabigatran is increasingly used to prevent
thromboembolic stroke in patients with atrial fibrillation (AF). Routine laboratory monitoring is …

Introduction The knowledge of dabigatran levels is helpful for decision‐making in specific
situations such as urgent surgery or when the question of reversal arises (uncontrolled …

Essentials• Routine monitoring is unnecessary but measuring dabigatran levels is helpful in
certain situations.• We compared ecarin chromogenic assay (STA‐ECA‐II) and dilute …

Background: Direct oral anticoagulants (DOAC) including edoxaban are increasingly used
for stroke prevention in atrial fibrillation. Despite treatment, annual stroke rate in these …