Noroviruses (NVs) are recognized as a major cause of nonbacterial gastroenteritis in
humans. Studies of the human NVs continue to be hampered by the inability to propagate …

Background Noroviruses are the leading cause of viral gastroenteritis. Because a suitable in
vitro culture system for the human virus has yet to be developed, many basic details of the …

Human norovirus (HNoV) is the leading cause of acute gastroenteritis and is spread by fecal
shedding that can often persist for weeks to months after the resolution of symptoms …

Investigations into human norovirus infection, replication and pathogenesis, as well as the
development of potential antiviral agents, have been restricted by the lack of a cell culture …

Calicivirus infection causes intrinsic apoptosis, leading to viral propagation in the host.
During murine norovirus infection, a reduction in the anti-apoptotic protein survivin has been …

Small RNA viruses have evolved many mechanisms to increase the capacity of their short
genomes. Here we describe the identification and characterization of a novel open reading …

Many viruses replicate most efficiently in specific phases of the cell cycle, establishing or
exploiting favorable conditions for viral replication, although little is known about the …

Subclinical infection of murine norovirus (MNV) was detected in a mixed breeding group of
WT and Stat1−/− mice with no outward evidence of morbidity or mortality. Investigations …

Murine norovirus (MNV), a prevalent pathogen of laboratory mice, shares many
characteristics with human noroviruses. Previous results indicated that passage of MNV1 in …

Human noroviruses (family Caliciviridae) are the leading cause of nonbacterial
gastroenteritis worldwide. Despite the prevalence of these viruses within the community, the …