Role of GABAB receptors in learning and memory and neurological disorders

CF Heaney, JW Kinney - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Although it is evident from the literature that altered GABA B receptor function does affect
behavior, these results often do not correspond well. These differences could be due to the …

[HTML][HTML] Differential compartmentalization and distinct functions of GABAB receptor variants

R Vigot, S Barbieri, H Bräuner-Osborne, R Turecek… - Neuron, 2006 - cell.com
GABA B receptors are the G protein-coupled receptors for the main inhibitory
neurotransmitter in the brain, γ-aminobutyric acid (GABA). Molecular diversity in the GABA B …

Specific roles of GABAB (1) receptor isoforms in cognition

LH Jacobson, PH Kelly, B Bettler, K Kaupmann… - Behavioural brain …, 2007 - Elsevier
The GABAB receptor is a heterodimer of GABAB (1) and GABAB (2) subunits. There are two
isoforms of the GABAB (1) subunit: GABAB (1a) and GABAB (1b). Recent studies with …

Roles of GABAB receptor subtypes in presynaptic auto- and heteroreceptor function regulating GABA and glutamate release

PC Waldmeier, K Kaupmann, S Urwyler - Journal of neural transmission, 2008 - Springer
Abstract Γ-Aminobutyric acid B (GABA B) receptors are heterodimers composed of two
subunits GABA B (1) and GABA B (2), the former existing in two isoforms GABA B (1a) and …

Historical perspective and emergence of the GABAB receptor

NG Bowery - Advances in pharmacology, 2010 - Elsevier
This chapter forms an introduction to the subsequent chapters in this volume which highlight
the significance and potential therapeutic application of GABA B receptors. It is now 30 years …

GABAB receptors: synaptic functions and mechanisms of diversity

D Ulrich, B Bettler - Current opinion in neurobiology, 2007 - Elsevier
GABAB receptors are the G-protein-coupled receptors for GABA, the main inhibitory
neurotransmitter in the mammalian central nervous system. They are implicated in a variety …

GABAB receptors and synaptic modulation

HC Kornau - Cell and tissue research, 2006 - Springer
GABA B receptors modulate transmitter release and postsynaptic membrane potential at
various types of central synapses. They function as heterodimers of two related seven …

[HTML][HTML] GABAB receptor constituents revealed by tandem affinity purification from transgenic mice

T Bartoi, KTG Rigbolt, D Du, G Köhr, B Blagoev… - Journal of Biological …, 2010 - ASBMB
GABA B receptors function as heterodimeric G-protein-coupled receptors for the
neurotransmitter γ-aminobutyric acid (GABA). Receptor subtypes, based on isoforms of the …

Redistribution of GABAB (1) protein and atypical GABAB responses in GABAB (2)-deficient mice

M Gassmann, H Shaban, R Vigot, G Sansig… - Journal of …, 2004 - Soc Neuroscience
GABAB receptors mediate slow synaptic inhibition in the nervous system. In transfected
cells, functional GABAB receptors are usually only observed after coexpression of GABAB …

The physiological properties and therapeutic potential of α5-GABAA receptors

LJ Martin, RP Bonin, BA Orser - Biochemical Society …, 2009 - portlandpress.com
The notion that drug treatments can improve memory performance has moved from the
realm of science fiction to that of serious investigation. A popular working hypothesis is that …