Considerations for the use of machine learning extracted real-world data to support evidence generation: a research-centric evaluation framework

M Estevez, CM Benedum, C Jiang, AB Cohen… - Cancers, 2022 - mdpi.com
Simple Summary Many patient clinical characteristics, such as diagnosis dates, biomarker
status, and therapies received, are only available as unstructured text in electronic health …

Replication of real-world evidence in oncology using electronic health record data extracted by machine learning

CM Benedum, A Sondhi, E Fidyk, AB Cohen, S Nemeth… - Cancers, 2023 - mdpi.com
Simple Summary Obtaining and structuring information about the characteristics, treatments,
and outcomes of people living with cancer for research purposes is difficult and resource …

Approach to machine learning for extraction of real-world data variables from electronic health records

B Adamson, M Waskom, A Blarre, J Kelly… - Frontiers in …, 2023 - frontiersin.org
Background: As artificial intelligence (AI) continues to advance with breakthroughs in natural
language processing (NLP) and machine learning (ML), such as the development of models …

Toward structuring real-world data: Deep learning for extracting oncology information from clinical text with patient-level supervision

S Preston, M Wei, R Rao, R Tinn, N Usuyama, M Lucas… - Patterns, 2023 - cell.com
Most detailed patient information in real-world data (RWD) is only consistently available in
free-text clinical documents. Manual curation is expensive and time consuming. Developing …

Natural language inference for curation of structured clinical registries from unstructured text

B Percha, K Pisapati, C Gao… - Journal of the American …, 2022 - academic.oup.com
Objective Clinical registries—structured databases of demographic, diagnosis, and
treatment information—play vital roles in retrospective studies, operational planning, and …

[HTML][HTML] Automating access to real-world evidence

MP Gauthier, JH Law, LW Le, JJN Li, S Zahir… - JTO Clinical and …, 2022 - Elsevier
Introduction Real-world evidence is important in regulatory and funding decisions. Manual
data extraction from electronic health records (EHRs) is time-consuming and challenging to …

[HTML][HTML] Generate Analysis-Ready Data for Real-world Evidence: Tutorial for Harnessing Electronic Health Records With Advanced Informatic Technologies

J Hou, R Zhao, J Gronsbell, Y Lin, CL Bonzel… - Journal of medical …, 2023 - jmir.org
Although randomized controlled trials (RCTs) are the gold standard for establishing the
efficacy and safety of a medical treatment, real-world evidence (RWE) generated from real …

[HTML][HTML] Toward better public health reporting using existing off the shelf approaches: A comparison of alternative cancer detection approaches using plaintext medical …

SN Kasthurirathne, BE Dixon, J Gichoya, H Xu… - Journal of biomedical …, 2016 - Elsevier
Objectives Increased adoption of electronic health records has resulted in increased
availability of free text clinical data for secondary use. A variety of approaches to obtain …

Challenges and opportunities beyond structured data in analysis of electronic health records

M Tayefi, P Ngo, T Chomutare… - Wiley …, 2021 - Wiley Online Library
Electronic health records (EHR) contain a lot of valuable information about individual
patients and the whole population. Besides structured data, unstructured data in EHRs can …

Hierarchical attention networks for information extraction from cancer pathology reports

S Gao, MT Young, JX Qiu, HJ Yoon… - Journal of the …, 2018 - academic.oup.com
Objective: We explored how a deep learning (DL) approach based on hierarchical attention
networks (HANs) can improve model performance for multiple information extraction tasks …