Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis

M Sata, D Fukuda - The Journal of Medical Investigation, 2010 - jstage.jst.go.jp
The renin-angiotensin system (RAS) has been demonstrated to play a critical role in the
initiation and progression of atherosclerosis, thereby contributing to development of …

[HTML][HTML] Inflammation, oxidative stress and renin angiotensin system in atherosclerosis

K Husain, W Hernandez, RA Ansari… - World journal of …, 2015 - ncbi.nlm.nih.gov
Atherosclerosis is a chronic inflammatory disease associated with cardiovascular
dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke …

Renin–angiotensin system as a therapeutic target in managing atherosclerosis

CM Ferrario, RS Richmond, R Smith… - American journal of …, 2004 - journals.lww.com
Clinical and experimental evidence suggests that the pathways by which hypertension and
dyslipidemia lead to vascular disease may overlap and that angiotensin II (Ang II) is involved …

Renin-angiotensin system in pathogenesis of atherosclerosis and treatment of CVD

AV Poznyak, D Bharadwaj, G Prasad… - International Journal of …, 2021 - mdpi.com
Atherosclerosis has complex pathogenesis, which involves at least three serious aspects:
inflammation, lipid metabolism alterations, and endothelial injury. There are no effective …

Role of renin-angiotensin system components in atherosclerosis: focus on Ang-II, ACE2, and Ang-1–7

GM Silva, MS França-Falcão, NTM Calzerra… - Frontiers in …, 2020 - frontiersin.org
Atherosclerosis is the leading cause of vascular disease worldwide and contributes
significantly to deaths from cardiovascular complications. There is a remarkably close …

The renin–angiotensin system and its involvement in vascular disease

BS van Thiel, I van der Pluijm, L te Riet, J Essers… - European journal of …, 2015 - Elsevier
The renin–angiotensin system (RAS) plays a critical role in the pathogenesis of many types
of cardiovascular diseases including cardiomyopathy, valvular heart disease, aneurysms …

Inhibition of renin–angiotensin system attenuates periadventitial inflammation and reduces atherosclerotic lesion formation

D Fukuda, S Enomoto, R Nagai, M Sata - Biomedicine & pharmacotherapy, 2009 - Elsevier
Recent evidence indicates that renin–angiotensin system (RAS) plays an important role in
the pathogenesis of atherosclerosis. It was reported that inhibition of RAS with angiotensin II …

The renin‐angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies

F Montecucco, A Pende, F Mach - Mediators of inflammation, 2009 - Wiley Online Library
Recent evidence shows that the renin‐angiotensin system is a crucial player in
atherosclerotic processes. The regulation of arterial blood pressure was considered from its …

Role of the renin-angiotensin system in vascular diseases: expanding the field

M Ruiz-Ortega, O Lorenzo, M Ruperez, V Esteban… - …, 2001 - Am Heart Assoc
The renin-angiotensin system (RAS) has emerged as one of the essential links in the
pathophysiology of vascular disease. Angiotensin (Ang) II, the main peptide of the RAS, was …

Regulation of the renin–angiotensin system in coronary atherosclerosis: a review of the literature

RA Hammoud, CS Vaccari, SH Nagamia… - Vascular health and …, 2007 - Taylor & Francis
Activation of the renin–angiotensin system (RAS) is significant in the pathogenesis of
cardiovascular disease and specifically coronary atherosclerosis. There is strong evidence …