Long-term benefits and harms associated with genetic cholesteryl ester transfer protein deficiency in the general population
LT Nordestgaard, M Christoffersen… - JAMA …, 2022 - jamanetwork.com
Importance The balance between the potential long-term clinical benefits and harms
associated with genetic cholesteryl ester transfer protein (CETP) deficiency, mimicking …
associated with genetic cholesteryl ester transfer protein (CETP) deficiency, mimicking …
A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester …
Y Moriyama, T Okamura, A Inazu, M Doi, H Iso… - Preventive …, 1998 - Elsevier
Background. Use of genetic analysis may improve the predictive value of risk factors for
disease. A high plasma level of high-density lipoprotein (HDL) cholesterol is a strong …
disease. A high plasma level of high-density lipoprotein (HDL) cholesterol is a strong …
Common cholesteryl ester transfer protein mutations, decreased HDL cholesterol, and possible decreased risk of ischemic heart disease: The Copenhagen City Heart …
B Agerholm-Larsen, A Tybjærg-Hansen, P Schnohr… - Circulation, 2000 - Am Heart Assoc
Background—Cholesteryl ester transfer protein (CETP) mediates the transfer of cholesteryl
ester from HDL in exchange for triglycerides in apolipoprotein B–containing lipoproteins …
ester from HDL in exchange for triglycerides in apolipoprotein B–containing lipoproteins …
Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk
A Thompson, E Di Angelantonio, N Sarwar, S Erqou… - Jama, 2008 - jamanetwork.com
Context The importance of the cholesteryl ester transfer protein (CETP) pathway in coronary
disease is uncertain. Study of CETP genotypes can help better understand the relevance of …
disease is uncertain. Study of CETP genotypes can help better understand the relevance of …
Common genetic variation of the cholesteryl ester transfer protein gene strongly predicts future cardiovascular death in patients with coronary artery disease
S Blankenberg, HJ Rupprecht, C Bickel… - Journal of the American …, 2003 - jacc.org
Objectives: We sought to evaluate the association between cholesteryl ester transfer protein
(CETP) genotypes and the risk of future cardiovascular mortality in patients with coronary …
(CETP) genotypes and the risk of future cardiovascular mortality in patients with coronary …
Genetic Inhibition of CETP, Ischemic Vascular Disease and Mortality, and Possible Adverse Effects
TH Johannsen, R Frikke-Schmidt, J Schou… - Journal of the American …, 2012 - jacc.org
Objectives: This study tested whether genetic variation in the CETP gene is consistent with a
protective effect of cholesteryl ester transfer protein (CETP) inhibition on risk of ischemic …
protective effect of cholesteryl ester transfer protein (CETP) inhibition on risk of ischemic …
Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene
B Agerholm-Larsen, BG Nordestgaard, R Steffensen… - Circulation, 2000 - Am Heart Assoc
Background—The level of HDL cholesterol is inversely related to the risk of ischemic heart
disease. Methods and Results—In 9168 women and men from a general population and …
disease. Methods and Results—In 9168 women and men from a general population and …
Cholesteryl Ester Transfer Protein Inhibition for Preventing Cardiovascular Events: JACC Review Topic of the Week
J Armitage, MV Holmes, D Preiss - Journal of the American College of …, 2019 - jacc.org
Cholesteryl ester transfer protein (CETP) facilitates exchange of triglycerides and cholesteryl
ester between high-density lipoprotein (HDL) and apolipoprotein B100–containing …
ester between high-density lipoprotein (HDL) and apolipoprotein B100–containing …
Is cholesteryl ester transfer protein inhibition an effective strategy to reduce cardiovascular risk? CETP inhibition as a strategy to reduce cardiovascular risk: the pro …
PJ Barter, SJ Nicholls, JJP Kastelein, KA Rye - Circulation, 2015 - Am Heart Assoc
424 Circulation August 4, 2015 lipoprotein particles in a process that equilibrates these
lipids between the different lipoprotein fractions. 3 Because most of the cholesteryl esters in …
lipids between the different lipoprotein fractions. 3 Because most of the cholesteryl esters in …
Association of CETP gene variants with risk for vascular and nonvascular diseases among Chinese adults
IY Millwood, DA Bennett, MV Holmes, R Boxall… - JAMA …, 2018 - jamanetwork.com
Importance Increasing levels of high-density lipoprotein (HDL) cholesterol through
pharmacologic inhibition of cholesteryl ester transfer protein (CETP) is a potentially …
pharmacologic inhibition of cholesteryl ester transfer protein (CETP) is a potentially …