Clinical Outcomes among Hospitalized COVID-19 Patients Who Received Baricitinib or Tocilizumab in Addition to Standard of Care

CP Walker, NP Hurlock, S Deb - Diseases, 2024 - mdpi.com
COVID-19 infection is caused by the novel severe acute respiratory syndrome coronavirus 2
(SAR-CoV-2). This novel virus has transformed into different resistant variants (eg, omicron; …

[HTML][HTML] Tocilizumab versus baricitinib in hospitalized patients with severe COVID-19: an open label, randomized controlled trial

T Karampitsakos, O Papaioannou, P Tsiri… - Clinical Microbiology …, 2023 - Elsevier
Objective Randomized controlled trials comparing tocilizumab and baricitinib in patients with
coronavirus disease 2019 (COVID-19) are needed. This was an open-label, randomized …

Baricitinib versus tocilizumab for the treatment of moderate to severe COVID-19

NK Reid, KR Joyner… - Annals of …, 2023 - journals.sagepub.com
Background: To date, minimal data directly compare tocilizumab with baricitinib for treatment
in moderate to severe COVID-19. Objective: To compare the rates of in-hospital mortality …

Impact of the addition of baricitinib to standard of care including tocilizumab and corticosteroids on mortality and safety in severe COVID-19

M Masiá, S Padilla, JA García, J García-Abellán… - Frontiers in …, 2021 - frontiersin.org
Background: Baricitinib is a Janus kinase (JAK) inhibitor with a broader anti-inflammatory
activity than tocilizumab and an antiviral potential although no head-to-head trials are …

Baricitinib versus tocilizumab in critically ill COVID‐19 patients: A retrospective cohort study

GM Conroy, SR Bauer, AM Pallotta… - … : The Journal of …, 2024 - Wiley Online Library
Objectives The immunomodulators tocilizumab and baricitinib improve outcomes in severely
ill patients with coronavirus disease 2019 (COVID‐19); however, comparative analyses of …

Comparison of Tocilizumab vs Baricitinib in Clinical Outcomes Among Hospitalized Patients With COVID-19: Experience From a Public Hospital System in New York …

S Sunny, A Tran, J Lee, M Abdallah… - Open Forum …, 2023 - academic.oup.com
Background Tocilizumab and baricitinib are immunomodulators that have been repurposed
for the treatment of coronavirus disease 2019 (COVID-19). Whether one medication should …

Outcomes and adverse effects of baricitinib versus tocilizumab in the management of severe COVID-19

JH Peterson, NS Paranjape, N Grundlingh… - Critical Care …, 2023 - journals.lww.com
Objectives: The National Institutes of Health and Infectious Diseases Society of America
guidelines recommend tocilizumab or baricitinib in the management of severe COVID-19 …

Efficacy and safety of baricitinib and tocilizumab in hospitalized patients with COVID-19: a comparison using systematic review and meta-analysis

JJ Cherian, M Eerike, BS Bagepally, S Das… - Frontiers in …, 2022 - frontiersin.org
Objective: This review was performed to compare the efficacy and safety among hospitalized
patients with COVID-19 who received baricitinib and those who received tocilizumab …

Efficacy and safety of tocilizumab and baricitinib among patients hospitalized for COVID-19: a systematic review and meta-analysis

J Zhang, X Fan, X Zhang, F Jiang, Y Wu… - Frontiers in …, 2023 - frontiersin.org
Introduction: Tocilizumab and baricitinib are recommended treatment options for COVID-19
patients with hyperinflammatory response; however, there is a lack of systematic review …

Comparative efficacy of tocilizumab and baricitinib administration in COVID-19 treatment: a retrospective cohort study

Y Kojima, S Nakakubo, N Takei, K Kamada… - Medicina, 2022 - mdpi.com
Background and Objectives: Tocilizumab and baricitinib have been observed to improve the
outcomes of patients with coronavirus disease 2019 (COVID-19). However, a comparative …