Elevated cytokine levels in plasma of patients with SARS-CoV-2 do not contribute to pulmonary microvascular endothelial permeability

A Kovacs-Kasa, AA Zaied, S Leanhart… - Microbiology …, 2022 - Am Soc Microbiol
The vascular endothelial injury occurs in severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infections, but the mechanisms are poorly understood. We sought to …

[HTML][HTML] Pathophysiological association of endothelial dysfunction with fatal outcome in COVID-19

T Maruhashi, Y Higashi - International Journal of Molecular Sciences, 2021 - mdpi.com
The outbreak of coronavirus disease 2019 (COVID-19) caused by the betacoronavirus
SARS-CoV-2 is now a worldwide challenge for healthcare systems. Although the leading …

[HTML][HTML] Markers of endothelial cell activation are associated with the severity of pulmonary disease in COVID-19

WO Osburn, K Smith, L Yanek, N Amat-Alcaron… - PLoS …, 2022 - journals.plos.org
Severe coronavirus disease-19 (COVID-19) is characterized by vascular inflammation and
thrombosis. We and others have proposed that the inflammatory response to coronavirus …

COVID-19–associated lung microvascular endotheliopathy: a “from the bench” perspective

J Joffre, L Rodriguez, ZA Matthay, E Lloyd… - American Journal of …, 2022 - atsjournals.org
Rationale: Autopsy and biomarker studies suggest that endotheliopathy contributes to
coronavirus disease (COVID-19)-associated acute respiratory distress syndrome. However …

[HTML][HTML] Endothelium infection and dysregulation by SARS-CoV-2: evidence and caveats in COVID-19

I Bernard, D Limonta, LK Mahal, TC Hobman - Viruses, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …

Circulating endothelial cells as a marker of endothelial injury in severe COVID-19

C Guervilly, S Burtey, F Sabatier… - The Journal of …, 2020 - academic.oup.com
Beside the commonly described pulmonary expression of the coronavirus disease 2019
(COVID-19), major vascular events have been reported. The objective of this study was to …

[HTML][HTML] Endothelial dysfunction and cardiovascular risk in post-COVID-19 patients after 6-and 12-months SARS-CoV-2 infection

P Poyatos, N Luque, G Sabater, S Eizaguirre, M Bonnin… - Infection, 2024 - Springer
Introduction SARS-CoV-2 infection causes severe endothelial damage, an essential step for
cardiovascular complications. Endothelial-colony forming cells (ECFCs) act as a biomarker …

Vascular endothelial damage in the pathogenesis of organ injury in severe COVID-19

A Dupont, A Rauch, S Staessens… - … and Vascular Biology, 2021 - Am Heart Assoc
Objective: Whether endotheliopathy only mirrors coronavirus disease 2019 (COVID-19)
severity or plays an intrinsic role in microvascular thrombosis and organ failure remains …

Endothelial injury in COVID-19 and septic patients

LT Hokama, ADM Veiga, MCS Menezes, AAS Pinto… - Microvascular …, 2022 - Elsevier
Systemic inflammatory response, as observed in sepsis and severe COVID-19, may lead to
endothelial damage. Therefore, we aim to compare the extent of endothelial injury and its …

[HTML][HTML] Long-term assessment of systemic microcirculatory function and plasma cytokines after coronavirus disease 2019 (COVID-19)

L Sabioni, AD Lorenzo… - Brazilian Journal of …, 2023 - SciELO Brasil
Systemic microvascular dysfunction has been shown to be present in COVID-19, and serum
cytokines are known to be involved in the regulation of vascular function. We sought to …