Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes

H Kaur, N Shekhar, S Sharma, P Sarma… - Pharmacological …, 2021 - Springer
Introduction COVID-19 cases are on surge; however, there is no efficient treatment or
vaccine that can be used for its management. Numerous clinical trials are being reviewed for …

Exploring the binding efficacy of ivermectin against the key proteins of SARS-CoV-2 pathogenesis: an in silico approach

A Choudhury, NC Das, R Patra, M Bhattacharya… - Future …, 2021 - Taylor & Francis
Aim: COVID-19 is currently the biggest threat to mankind. Recently, ivermectin (a US FDA-
approved antiparasitic drug) has been explored as an anti-SARS-CoV-2 agent. Herein, we …

Ivermectin as a potential COVID-19 treatment from the pharmacokinetic point of view: antiviral levels are not likely attainable with known dosing regimens

G Momekov, D Momekova - Biotechnology & biotechnological …, 2020 - Taylor & Francis
The broad-spectrum antiparasitic agent ivermectin has been very recently found to inhibit
SARS-CoV-2 in vitro and proposed as a candidate for drug repurposing in COVID-19. In the …

Molecular docking reveals ivermectin and remdesivir as potential repurposed drugs against SARS-CoV-2

AF Eweas, AA Alhossary… - Frontiers in Microbiology, 2021 - frontiersin.org
SARS-CoV-2 is a newly emerged coronavirus that causes a respiratory disease with
variable severity and fatal consequences. It was first reported in Wuhan and subsequently …

An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α

F Azam, IM Taban, EEM Eid, M Iqbal… - Journal of …, 2022 - Taylor & Francis
Ivermectin (IVM) is a broad-spectrum antiparasitic agent, having inhibitory potential against
wide range of viral infections. It has also been found to hamper SARS-CoV-2 replication in …

Therapeutic potential of ivermectin as add on treatment in COVID 19: A systematic review and meta-analysis: Ivermectin in COVID-19: A meta-analysis

BM Padhy, RR Mohanty, S Das… - Journal of Pharmacy …, 2020 - journals.library.ualberta.ca
The current management of COVID-19 is mostly limited to general supportive care and
symptomatic treatment. Ivermectin is a broad-spectrum anti-parasitic drug used widely for …

A systematic review of experimental evidence for antiviral effects of ivermectin and an in silico analysis of ivermectin's possible mode of action against SARS‐CoV‐2

RT Kinobe, L Owens - Fundamental & clinical pharmacology, 2021 - Wiley Online Library
Viral infections remain a major cause of economic loss with an unmet need for novel
therapeutic agents. Ivermectin is a putative antiviral compound; the proposed mechanism is …

Ivermectin: an award-winning drug with expected antiviral activity against COVID-19

FR Formiga, R Leblanc, J de Souza Rebouças… - Journal of controlled …, 2021 - Elsevier
Ivermectin is an FDA-approved broad-spectrum antiparasitic agent with demonstrated
antiviral activity against a number of DNA and RNA viruses, including severe acute …

Ivermectin and outcomes from Covid‐19 pneumonia: a systematic review and meta‐analysis of randomized clinical trial studies

TI Hariyanto, DA Halim, J Rosalind… - Reviews in medical …, 2022 - Wiley Online Library
Ivermectin is an FDA‐approved drug for a parasitic disease that has broad antiviral activity.
This study aims to analyse the efficacy of ivermectin in improving the Covid‐19 outcomes …

[HTML][HTML] Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen

F Heidary, R Gharebaghi - The Journal of antibiotics, 2020 - nature.com
Ivermectin proposes many potentials effects to treat a range of diseases, with its
antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective …