The role of lncRNAs in innate immunity and inflammation

K Walther, LN Schulte - RNA biology, 2021 - Taylor & Francis
The innate immune system relies on a germ-line-encoded repertoire of pattern recognition
receptors (PRRs), activated by deeply conserved pathogen signatures, such as bacterial cell …

Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression

R Elling, J Chan, KA Fitzgerald - European journal of …, 2016 - Wiley Online Library
The innate immune system represents the first line of defense during infection and is
initiated by the detection of conserved microbial products by germline‐encoded pattern …

Long noncoding RNAs in host–pathogen interactions

F Agliano, VA Rathinam, AE Medvedev, SK Vanaja… - Trends in …, 2019 - cell.com
Long noncoding RNAs (lncRNAs) are key molecules that regulate gene expression in a
variety of organisms. LncRNAs can drive different transcriptional and post-transcriptional …

Long noncoding RNAs and the regulation of innate immunity and host-virus interactions

M Basavappa, S Cherry… - Journal of leukocyte …, 2019 - academic.oup.com
Immune responses are both pathogen and cell type-specific. The innate arm of immunity is
characterized by rapid intracellular signaling cascades resulting in the production of …

Decoding the noncoding: prospective of lncRNA-mediated innate immune regulation

Z Li, TM Rana - RNA biology, 2014 - Taylor & Francis
The innate immune system is the first line of defense against microbial pathogens, but tight
regulation of gene expression is necessary to prevent the detrimental effects of unrestrained …

[HTML][HTML] Long non-coding RNAs and the innate immune response

MR Hadjicharalambous, MA Lindsay - Non-coding RNA, 2019 - mdpi.com
Innate immunity provides the initial defence against infection and it is now clear that long
non-coding RNAs (lncRNAs) are important regulators of this response. Following activation …

Long noncoding RNA: novel links between gene expression and innate immunity

S Carpenter - Virus research, 2016 - Elsevier
Protection against infection and maintenance of homeostasis are the hallmarks of the innate
immune system. The complex signaling cascades that occur following microbial infection …

[HTML][HTML] A novel regulatory player in the innate immune system: long non-coding RNAs

Y Xie, Y Wei - International journal of molecular sciences, 2021 - mdpi.com
Long non-coding RNAs (lncRNAs) represent crucial transcriptional and post-transcriptional
gene regulators during antimicrobial responses in the host innate immune system. Studies …

lncRNAs regulate innate immune responses and their roles in macrophage polarization

Z Wang, Y Zheng - Mediators of inflammation, 2018 - Wiley Online Library
The innate immune system is the first line of defense against microbial pathogens. The
activated innate immune system plays important roles in eliciting antimicrobial defenses …

Long non-coding RNAs in antiviral immunity

T Vierbuchen, KA Fitzgerald - Seminars in Cell & Developmental Biology, 2021 - Elsevier
Tight regulation of the immune response is fundamental for efficient pathogen clearance and
to prevent excessive inflammation. Long non-coding RNAs (lncRNAs) have emerged as …