Heparin: an established anticoagulant drug with therapeutic potential for COVID-19

OG McIntosh - 2022 - keele-repository.worktribe.com
The biologically and medically important heparan sulphate and heparin polysaccharides
have been previously shown to mediate viral cell entry for enveloped viruses. Furthermore …

Comprehensive landscape of heparin therapy for COVID-19

C Shi, W Tingting, JP Li, MA Sullivan, C Wang… - Carbohydrate …, 2021 - Elsevier
The pandemic coronavirus disease 2019 (COVID-19), caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading globally …

[HTML][HTML] Heparin–an old drug with multiple potential targets in Covid‐19 therapy

U Lindahl, JP Li - Journal of Thrombosis and Haemostasis, 2020 - jthjournal.org
2. Dianne K, Jennings I, Kitchen S, Walker I. Letter in response to article “Systematic review
of viscoelastic testing (TEG/Rotem) in obstetrics and recommendations from the women's …

An Evaluation of the Potential of Heparin to Inhibit the Viral Entry of SARS-CoV-2

S Samadder, P Anto Johnson… - Canadian Journal of …, 2021 - cjm.cikd.ca
Heparin is an anticoagulant medicine that prevents the formation of harmful blood clots in
the vessels. Following the outbreak of the novel coronavirus disease 2019 (COVID-19) …

Another new application of heparin in COVID-19: more than anticoagulation and antiviral

X Yu - Journal of Investigative Medicine, 2021 - authorea.com
Heparin is used as a classic anticoagulant in clinic. In addition, with the ongoing pandemic
and unknown challenges, the mechanism of action of heparin in antiviral and anti …

Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations

JA Tree, JE Turnbull, KR Buttigieg… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Currently, there are no licensed vaccines and limited antivirals for
the treatment of COVID‐19. Heparin (delivered systemically) is currently used to treat …

[HTML][HTML] The benefits of heparin use in COVID-19: pleiotropic antiviral activity beyond anticoagulant and anti-inflammatory properties

G Lippi, BM Henry, EJ Favaloro - Seminars in Thrombosis and …, 2023 - thieme-connect.com
Coronavirus disease 2019 (COVID-19), a life-threatening infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing the worst …

Using heparin molecules to manage COVID‐2019

J Liu, J Li, K Arnold, R Pawlinski… - Research and practice …, 2020 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic is becoming one of the
largest global public health crises in modern history. The race for an effective drug to prevent …

[PDF][PDF] Using heparin molecules to manage COVID-2019

NS Key - scienceopen.com
Abstract The COVID-19 (coronavirus disease 2019) pandemic is becoming one of the
largest global public health crises in modern history. The race for an effective drug to prevent …

Heparin as a therapy for COVID-19: current evidence and future possibilities

JA Hippensteel, WB LaRiviere… - … of Physiology-Lung …, 2020 - journals.physiology.org
Coronavirus disease 2019 (COVID-19), the clinical syndrome associated with infection by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted nearly every …