In the last years, proteomics has represented a valuable approach to elucidate key aspects
in the regulation of type I/III interferons (IFNs) and autophagy, two main processes involved …

Viruses manipulate cellular machinery and functions to subvert intracellular environment
conducive for viral proliferation. They strategically alter functions of the multitasking …

Mitochondria are dynamic organelles vital for energy production with now appreciated roles
in immune defense. During microbial infection, mitochondria serve as signaling hubs to …

The innate immune system has a key role in the mammalian immune response. In the
cytosol, RNA viruses are sensed by the retinoic acid‐inducible gene‐I‐like receptors, which …

Mitochondria, the dynamic organelles and power house of eukaryotic cells function as
metabolic hubs of cells undergoing continuous cycles of fusion and fission. Recent findings …

Mitochondria are master regulators of metabolism and have emerged as key signalling
organelles of the innate immune system. Each mitochondrion harbours potent agonists of …

Mitochondria, cellular powerhouses of eukaryotes, are known to act as central hubs for
multiple signal transductions. Recent research reveals that mitochondria are involved in …

Mitochondria have emerged as critical platforms for antiviral innate immune signaling. This
is due in large part to the mitochondrial localization of the innate immune signaling adaptor …

Viruses have developed a battery of distinct strategies to overcome the very sophisticated
defense mechanisms of the infected host. Throughout the process of pathogen–host co …

Regulation of mitochondrial structure and function is a central component of infection with
viruses, including human cytomegalovirus (HCMV), as a virus means to modulate cellular …