This thesis, after a review on the state-of-the-art sequencing and genotyping technologies,
focuses on the semiconductor-based systems using pH change for DNA (Deoxyribonucleic …

Ion sensitive field-effect transistor in DNA sequencing application is gaining popularity
because of its capability to work massive parallel sensor arrays, especially when integrated …

This paper presents a novel configuration for Ion sensitive Field Effect Transistors (ISFETs)
to be used as a threshold detector during a Single Nucleotide Polymorphism (SNP) base …

The advent of complementary metal-oxide-semiconductor (CMOS) based lab-on-chip (LoC)
technology, which combines on-chip sample handling with integrated sensing, heralds the …

CMOS (complementary metal oxide semiconductor) biosensors are promising to provide
label-free and highly sensitive detection with high throughput. Ion-sensitive field effect …

In the last decade the use of field-effect-based devices has become a basic structural
element in a new generation of biosensors that allow label-free DNA analysis. In particular …

Field effect transistors are considered one of the key technologies to provide real-time and
label-free biodetection. Direct detection in physiological solutions is, however, severely …

This letter reports a large complementary metal-oxide semiconductor DNA array with more
than 1000 sensors to demonstrate sensitive and wide-range detection under strong Debye …

In this paper we present a new sensing concept for ISFET based on pH-to-current
conversion. The high sensitivity of our proposed pH-to-current ISFET is achieved by …

This paper presents an ISFET-based front-end to detect DNA homopolymerisms in ion-
semiconductor sequencing. This is realised using a novel ISFET-based switched current …