Stigmasterol restores the balance of Treg/Th17 cells by activating the butyrate-PPARγ axis in colitis
S Wen, L He, Z Zhong, R Zhao, S Weng, H Mi… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with gut microbiota
disequilibrium and regulatory T (Treg)/T helper 17 (Th17) immune imbalance. Stigmasterol …
disequilibrium and regulatory T (Treg)/T helper 17 (Th17) immune imbalance. Stigmasterol …
Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats
M Zhang, Q Zhou, RG Dorfman, X Huang, T Fan… - BMC …, 2016 - Springer
Background Butyrate is an energy source for colonocytes that is formed by bacterial
fermentation of dietary fiber in the colon and that exerts broad anti-inflammatory activities …
fermentation of dietary fiber in the colon and that exerts broad anti-inflammatory activities …
Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells
Inflammatory diseases of the gastrointestinal tract are often associated with microbial
dysbiosis. Thus, dietary interactions with intestinal microbiota, to maintain homeostasis, play …
dysbiosis. Thus, dietary interactions with intestinal microbiota, to maintain homeostasis, play …
Microbiota metabolite butyrate differentially regulates Th1 and Th17 cells' differentiation and function in induction of colitis
Background How the gut microbiota regulates intestinal homeostasis is not completely clear.
Gut microbiota metabolite short-chain fatty acids (SCFAs) have been reported to regulate T …
Gut microbiota metabolite short-chain fatty acids (SCFAs) have been reported to regulate T …
[HTML][HTML] Flos Abelmoschus manihot extract attenuates DSS-induced colitis by regulating gut microbiota and Th17/Treg balance
W Zhang, C Cheng, Q Han, Y Chen, J Guo… - Biomedicine & …, 2019 - Elsevier
Flos Abelmoschus manihot is widely used as traditional drug in China. Abelmoschus
manihot (AM) extracted from Flos Abelmoschus manihot that has been applied for treating …
manihot (AM) extracted from Flos Abelmoschus manihot that has been applied for treating …
[HTML][HTML] The effect of 6-gingerol on inflammatory response and Th17/Treg balance in DSS-induced ulcerative colitis mice
Y Sheng, T Wu, Y Dai, K Ji, Y Zhong… - Annals of translational …, 2020 - ncbi.nlm.nih.gov
Background Ulcerative colitis (UC) is a non-specific chronic intestinal inflammatory disease
with unclear etiology. Previous studies have suggested that the imbalance of Treg/Thl7 cells …
with unclear etiology. Previous studies have suggested that the imbalance of Treg/Thl7 cells …
Metformin ameliorates inflammatory bowel disease by suppression of the STAT3 signaling pathway and regulation of the between Th17/Treg balance
SY Lee, SH Lee, EJ Yang, EK Kim, JK Kim, DY Shin… - PloS one, 2015 - journals.plos.org
Objective Metformin is used to treat type 2 diabetes. We sought to determine whether
metformin reduces inflammation, by regulating p-signal transducer and activator of …
metformin reduces inflammation, by regulating p-signal transducer and activator of …
Berberine regulates Treg/Th17 balance to treat ulcerative colitis through modulating the gut microbiota in the colon
H Cui, Y Cai, L Wang, B Jia, J Li, S Zhao… - Frontiers in …, 2018 - frontiersin.org
Berberine (BBR), an alkaloid isolated from Rhizoma Coptidis, Cortex Phellode, and
Berberis, has been widely used in the treatment of ulcerative colitis (UC). However, the …
Berberis, has been widely used in the treatment of ulcerative colitis (UC). However, the …
[HTML][HTML] Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22–dependent manner
Colitis, an inflammatory bowel disease, is caused by a variety of factors, but luminal
microbiota are thought to play crucial roles in disease development and progression. Indole …
microbiota are thought to play crucial roles in disease development and progression. Indole …
Treatment with butyrate alleviates dextran sulfate sodium and Clostridium difficile-induced colitis by preventing activity of Th17 cells via regulation of SIRT1/mTOR in …
S Wang, W Deng, F Li, L Xiang, P Lv, Y Chen - The Journal of Nutritional …, 2023 - Elsevier
Inflammatory bowel disease (IBD) patients are particularly vulnerable to infection with
Clostridium difficile infection (CDI). Available treatments of IBD with CDI have not effective …
Clostridium difficile infection (CDI). Available treatments of IBD with CDI have not effective …