Tetraspanins are transmembrane glycoproteins that have been shown increasing interest as
host factors in infectious diseases. In particular, they were implicated in the pathogenesis of …

The tetraspanins are a broadly expressed superfamily of transmembrane glycoproteins with
over 30 members found in humans and with homologues conserved through distantly …

Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma
membrane “master organizers.” They form Tspan-enriched microdomains (TEMs or TERMs) …

Tetraspanin proteins on host cells are involved in the pathogenesis of infectious diseases at
different stages. In this review, we will focus on tetraspanins expressed in the immune …

Tetraspanins are suggested to regulate the composition of cell membrane components and
control intracellular transport, which leaves them vulnerable to utilization by pathogens such …

The identification of novel targets and strategies for therapy of microbial infections is an area
of intensive research due to the failure of conventional vaccines or antibiotics to combat both …

The tetraspanins constitute a conserved superfamily of four-span membrane proteins that
are widely distributed in multi-cellular organisms. A characteristic property of tetraspanins is …

Members of the tetraspanin family have been identified as essential cellular membrane
proteins in infectious diseases by nearly all types of pathogens. The present review …

Despite the great research effort placed during the last decades in HIV-1 study, still some
aspects of its replication cycle remain unknown. All this powerful research has succeeded in …

Background The presence of the tetraspanins CD9, CD63, CD81 and CD82 at HIV-1
budding sites, at the virological synapse (VS), and their enrichment in HIV-1 virions has …