Oxidative dysregulation in early life stress and posttraumatic stress disorder: a comprehensive review

E Karanikas, NP Daskalakis, A Agorastos - Brain Sciences, 2021 - mdpi.com
Traumatic stress may chronically affect master homeostatic systems at the crossroads of
peripheral and central susceptibility pathways and lead to the biological embedment of …

Severe life stress and oxidative stress in the brain: from animal models to human pathology

S Schiavone, V Jaquet, L Trabace… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: Severe life stress (SLS), as opposed to trivial everyday stress, is defined as a
serious psychosocial event with the potential of causing an impacting psychological …

New Metabolic, Digestive, and Oxidative Stress‐Related Manifestations Associated with Posttraumatic Stress Disorder

BA Oroian, A Ciobica, D Timofte… - Oxidative Medicine …, 2021 - Wiley Online Library
Posttraumatic stress disorder (PTSD) represents a pressing and generally invalidating
syndrome that is triggered by a terrifying or stressful experience, relying on recurrently …

Oxidative stress in immature brain after traumatic brain injury

H Bayır, PM Kochanek, VE Kagan - Developmental neuroscience, 2006 - karger.com
High oxygen demand along with the abundance of readily oxidizable substrates yielding
productive oxidative metabolism are required for the normal function of the brain. This …

Defining the nuanced nature of redox biology in post-traumatic stress disorder

EC Reed, AJ Case - Frontiers in Physiology, 2023 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a mental health disorder that arises after
experiencing or witnessing a traumatic event. Despite affecting around 7% of the population …

Oxidative stress in anxiety and comorbid disorders

I Hovatta, J Juhila, J Donner - Neuroscience research, 2010 - Elsevier
Anxiety disorders, depression, and alcohol use disorder are common neuropsychiatric
diseases that often occur together. Oxidative stress has been suggested to contribute to their …

Common biochemical defects linkage between post-traumatic stress disorders, mild traumatic brain injury (TBI) and penetrating TBI

KN Prasad, SC Bondy - Brain research, 2015 - Elsevier
Post-traumatic stress disorder (PTSD) is a complex mental disorder with psychological and
emotional components, caused by exposure to single or repeated extreme traumatic events …

Good stress, bad stress and oxidative stress: insights from anticipatory cortisol reactivity

K Aschbacher, A O'Donovan, OM Wolkowitz… - …, 2013 - Elsevier
Chronic psychological stress appears to accelerate biological aging, and oxidative damage
is an important potential mediator of this process. However, the mechanisms by which …

In major affective disorders, early life trauma predict increased nitro-oxidative stress, lipid peroxidation and protein oxidation and recurrence of major affective …

JB Moraes, M Maes, C Roomruangwong… - Metabolic brain …, 2018 - Springer
Early life trauma (ELT) may increase the risk towards bipolar disorder (BD) and major
depression (MDD), disorders associated with activated neuro-oxidative and neuro …

Oxidative stress–assassin behind the ischemic stroke

H Pradeep, JB Diya, S Shashikumar… - Folia …, 2012 - termedia.pl
Ischemic stroke is the second leading cause of death and disability worldwide and is
associated with significant clinical and socioeconomic implications, emphasizing the need …