Non-coding RNAs regulation of macrophage polarization in cancer

S Mohapatra, C Pioppini, B Ozpolat, GA Calin - Molecular cancer, 2021 - Springer
Noncoding RNA (ncRNA) transcripts that did not code proteins but regulate their functions
were extensively studied for the last two decades and the plethora of discoveries have …

LncRNA-MM2P identified as a modulator of macrophage M2 polarization

JI Cao, R Dong, L Jiang, Y Gong, M Yuan, J You… - Cancer immunology …, 2019 - AACR
M2 polarization of macrophages is essential for their function in immunologic tolerance,
which might promote tumorigenesis. However, the molecular mechanism behind the …

[HTML][HTML] The impact of non-coding RNAs on macrophage polarization

S Ghafouri-Fard, A Abak, ST Avval, H Shoorei… - Biomedicine & …, 2021 - Elsevier
Macrophage polarization is a process through which macrophages attain unique functional
features as a response to certain stimuli from their niche. Lipopolysaccharide and Th1 …

Non-coding RNAs and macrophage interaction in tumor progression

M Entezari, M Sadrkhanloo, M Rashidi, SE Asnaf… - Critical reviews in …, 2022 - Elsevier
The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …

[HTML][HTML] Major pathways involved in macrophage polarization in cancer

C Kerneur, CE Cano, D Olive - Frontiers in immunology, 2022 - frontiersin.org
Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Tumor-associated macrophages as a paradigm of macrophage plasticity, diversity, and polarization: lessons and open questions

A Mantovani, M Locati - Arteriosclerosis, thrombosis, and vascular …, 2013 - Am Heart Assoc
Macrophages are present in all body compartments, including cancerous tissues, and their
functions are profoundly affected by signals from the microenvironment under homeostatic …

Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155

X Cai, Y Yin, N Li, D Zhu, J Zhang… - Journal of molecular …, 2012 - academic.oup.com
Dear Editor, A significant macrophage population has been detected within almost all
human and mouse tumors. These tumorassociated macrophages (TAMs) are critical …

Long noncoding RNA s as regulators of cancer immunity

N Denaro, MC Merlano, C Lo Nigro - Molecular oncology, 2019 - Wiley Online Library
Long noncoding RNA s (lnc RNA s) are increasingly known to be important in cancer as they
directly interact with the cell cycle, proliferation pathways and microbiome balance …

[HTML][HTML] Exosomal MicroRNAs as mediators of cellular interactions between cancer cells and macrophages

Y Kwon, M Kim, Y Kim, HS Jung, D Jeoung - Frontiers in immunology, 2020 - frontiersin.org
Tumor microenvironment consists of cancer cells and various stromal cells such as
endothelial cells, cancer-associated fibroblasts (CAFs), myeloid-derived suppressor cells …

miRNAs and lncRNAs as novel therapeutic targets to improve cancer immunotherapy

MT Di Martino, C Riillo, F Scionti, K Grillone, N Polerà… - Cancers, 2021 - mdpi.com
Simple Summary Cancer onset and progression are promoted by high deregulation of the
immune system. Recently, major advances in molecular and clinical cancer immunology …