Preparation of tannic acid and l-cysteine functionalized magnetic composites for synergistic enrichment of N-glycopeptides followed by mass spectrometric analysis

Y Wang, W Xu, H Xu, Q Jia - Analytical Methods, 2022 - pubs.rsc.org
Glycoprotein is involved in a variety of biological activities and has been linked to a number
of diseases. Glycopeptide enrichment prior to mass spectrometry (MS) detection is crucial to …

Synthesis of magnetic zwitterionic–hydrophilic material for the selective enrichment of N-linked glycopeptides

Y Zhao, Y Chen, Z Xiong, X Sun, Q Zhang… - … of chromatography A, 2017 - Elsevier
In consideration of the close connection between glycopeptides and human diseases, the
efficient method to separate and enrich glycopeptides from complex biological samples is …

Thiol-ene click synthesis of L-cysteine-bonded zwitterionic hydrophilic magnetic nanoparticles for selective and efficient enrichment of glycopeptides

R Wu, Y Xie, C Deng - Talanta, 2016 - Elsevier
Efficient and specific enrichment of low-abundant glycopeptides from complex biological
samples is essential to glycoproteomics analysis. Herein, novel magnetic zwitterionic …

Design and fabrication of highly hydrophilic magnetic material by anchoring l-cysteine onto chitosan for efficient enrichment of glycopeptides

B Zhao, W Xu, J Ma, Q Jia - Chinese Chemical Letters, 2023 - Elsevier
Hydrophilic interaction liquid chromatography (HILIC) has been recognized as an effective
strategy for glycopeptide enrichment. Hydrophilic materials pave the way to solve the limit of …

Facile synthesis of thiol-polyethylene glycol functionalized magnetic titania nanomaterials for highly efficient enrichment of N-linked glycopeptides

J Wang, J Yao, N Sun, C Deng - Journal of Chromatography A, 2017 - Elsevier
As protein N-glycosylation involved in generation and development of various cancers and
diseases, it is vital to capture glycopeptides from complex biological samples for biomarker …

Hydrazide Functionalized Core–Shell Magnetic Nanocomposites for Highly Specific Enrichment of N-Glycopeptides

L Liu, M Yu, Y Zhang, C Wang, H Lu - ACS applied materials & …, 2014 - ACS Publications
In view of the biological significance of glycosylation for human health, profiling of
glycoproteome from complex biological samples is highly inclined toward the discovery of …

Facile preparation of hydrophilic glutathione modified magnetic nanomaterials for specific enrichment of glycopeptides

H Qi, Z Li, H Zheng, L Fu, Q Jia - Chinese Chemical Letters, 2019 - Elsevier
Investigations of glycosylated proteins or peptides and their related biological pathways
provide new possibilities for illuminating the physiological and pathological mechanisms of …

Hydrophilic carrageenan functionalized magnetic carbon‐based framework linked by silane coupling agent for the enrichment of N‐glycopeptides from human saliva

X Jin, C Zhu, J Wu, Y Yan, CF Ding… - Journal of …, 2021 - Wiley Online Library
In this work, a magnetic graphene material coated with mesoporous silica was selected as
the substrate, 3‐glycidoxypropyltrimethoxysilane and polyethyleneimine were sequentially …

Facile and easily popularized synthesis of l-cysteine-functionalized magnetic nanoparticles based on one-step functionalization for highly efficient enrichment of …

X Feng, C Deng, M Gao, X Zhang - Analytical and bioanalytical chemistry, 2018 - Springer
Protein glycosylation is one of the most important post-translational modifications. Also,
efficient enrichment and separation of glycopeptides from complex samples are crucial for …

A magnetic nanofiber-based zwitterionic hydrophilic material for the selective capture and identification of glycopeptides

W Huan, J Zhang, H Qin, F Huan, B Wang, M Wu, J Li - Nanoscale, 2019 - pubs.rsc.org
High-performance affinity materials are highly required in the sample preparation process in
mass spectrometry-based glycoproteomics studies. In this research, a novel magnetic …