Effect of the ADRB1 1165C>G and 145A>G polymorphisms on hemodynamic response during dobutamine stress echocardiography

A Banaś, E Płońska, M Kurzawski, W Gornik… - European journal of …, 2011 - Springer
Purpose The aim of this study was to determine an association between the ADRB1 1165C>
G and 145A> G polymorphisms and hemodynamic response [heart rate (HR), systolic (SBP) …

Effects of sex and the common ADRB1 389 genetic polymorphism on the hemodynamic response to dobutamine

D Yogev, M Basheer, S Blotnick, Y Caraco… - Pharmacogenetics …, 2015 - journals.lww.com
Results Resting heart rate (HR) response to 6 mcg/kg/min dobutamine (ΔHR) was 4.7-fold
larger in Arg389Arg than in Gly389Gly [(mean±SD) 12.95±6.99, 2.75±1.65 bpm …

β-Adrenergic receptor gene polymorphisms and hemodynamic response to dobutamine during dobutamine stress echocardiography

CL Aquilante, HN Yarandi, LH Cavallari… - The …, 2008 - nature.com
Our objective was to determine if β 1-adrenergic receptor (β 1-AR) and β 2-AR gene
polymorphisms influence heart rate (HR), systolic blood pressure (SBP) and diastolic blood …

Functional effects of β1-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without β-blocker administration

M Kindermann, U Seeland, P Ruhnke, M Böhm… - Clinical Research in …, 2011 - Springer
Background The relevance of the Arg389Gly-and Ser49Gly-β 1-adrenoceptor (AR)
polymorphisms for cardiovascular function and pharmacotherapy is controversial. Methods …

Influence of 825 C> T polymorphism of G protein β subunit gene (GNB3) on hemodynamic response during dobutamine stress echocardiography

A Banaś, E Płońska, B Larysz, M Kurzawski… - Pharmacological …, 2012 - Springer
There is a wide interpersonal difference to dobutamine response during dobutamine stress
echocardiography (DSE). The aim of this study was to determine an association between …

Association of common polymorphisms in β1-adrenergic receptor with antihypertensive response to carvedilol

D Si, J Wang, Y Xu, X Chen, M Zhang… - Journal of …, 2014 - journals.lww.com
Objectives: Marked interpatient variability exists in the blood pressure response to
carvedilol, a nonselective β-blocker. Here we evaluated the influence of 4 common …

[HTML][HTML] Genetic polymorphisms in ADRB1, ADRB2 and CYP2D6 genes and response to beta-blockers in patients with acute coronary syndrome

C Castaño-Amores, A Antúnez-Rodríguez… - Biomedicine & …, 2023 - Elsevier
Betablockers (BBs) are prescribed for ischaemia in patients with acute coronary syndrome
(ACS). In Spain, bisoprolol and carvedilol are the most prescribed BBs, but patients often …

The common Arg389gly ADRB1 polymorphism affects heart rate response to the ultra-short-acting β1 adrenergic receptor antagonist esmolol in healthy individuals

M Muszkat, A Hoofien, E Orlanski-Meyer… - Pharmacogenetics …, 2013 - journals.lww.com
The β1-adrenergic receptor (β1AR) Arg389Gly polymorphism affects responses to orally
administered β1AR antagonists (β-blockers) in vivo. However, the effect of this …

The Arg389Gly β1-adrenoceptor gene polymorphism influences the acute effects of β-adrenoceptor blockade on contractility in the human heart

M Huntgeburth, K La Rosée, H Ten Freyhaus… - Clinical Research in …, 2011 - Springer
Background The β 1-adrenoceptor (β 1 AR) mediates cardiostimulatory effects of
catecholamines in the heart. The Arg389Gly polymorphism of the β 1 AR gene has recently …

Arg389Gly polymorphism of the human β1-adrenergic receptor in patients with nonfatal acute myocardial infarction

C Iwai, H Akita, K Kanazawa, N Shiga… - American heart …, 2003 - Elsevier
BACKGROUND: We sought to investigate the relation between the Arg389Gly
polymorphism in the human β1-adrenergic receptor (ADRB1) gene and acute myocardial …