D Yogev, M Basheer, S Blotnick, Y Caraco… - Pharmacogenetics …, 2015 - journals.lww.com
Results Resting heart rate (HR) response to 6 mcg/kg/min dobutamine (ΔHR) was 4.7-fold larger in Arg389Arg than in Gly389Gly [(mean±SD) 12.95±6.99, 2.75±1.65 bpm …
M Kindermann, U Seeland, P Ruhnke, M Böhm… - Clinical Research in …, 2011 - Springer
Background The relevance of the Arg389Gly-and Ser49Gly-β 1-adrenoceptor (AR) polymorphisms for cardiovascular function and pharmacotherapy is controversial. Methods …
A Banaś, E Płońska, B Larysz, M Kurzawski… - Pharmacological …, 2012 - Springer
There is a wide interpersonal difference to dobutamine response during dobutamine stress echocardiography (DSE). The aim of this study was to determine an association between …
D Si, J Wang, Y Xu, X Chen, M Zhang… - Journal of …, 2014 - journals.lww.com
Objectives: Marked interpatient variability exists in the blood pressure response to carvedilol, a nonselective β-blocker. Here we evaluated the influence of 4 common …
C Castaño-Amores, A Antúnez-Rodríguez… - Biomedicine & …, 2023 - Elsevier
Betablockers (BBs) are prescribed for ischaemia in patients with acute coronary syndrome (ACS). In Spain, bisoprolol and carvedilol are the most prescribed BBs, but patients often …
M Muszkat, A Hoofien, E Orlanski-Meyer… - Pharmacogenetics …, 2013 - journals.lww.com
The β1-adrenergic receptor (β1AR) Arg389Gly polymorphism affects responses to orally administered β1AR antagonists (β-blockers) in vivo. However, the effect of this …
M Huntgeburth, K La Rosée, H Ten Freyhaus… - Clinical Research in …, 2011 - Springer
Background The β 1-adrenoceptor (β 1 AR) mediates cardiostimulatory effects of catecholamines in the heart. The Arg389Gly polymorphism of the β 1 AR gene has recently …
C Iwai, H Akita, K Kanazawa, N Shiga… - American heart …, 2003 - Elsevier
BACKGROUND: We sought to investigate the relation between the Arg389Gly polymorphism in the human β1-adrenergic receptor (ADRB1) gene and acute myocardial …