The lncRNA 'UCA1'modulates the response to chemotherapy of ovarian cancer through direct binding to miR‐27a‐5p and control of UBE2N levels

A Wambecke, M Ahmad, PM Morice… - Molecular …, 2021 - Wiley Online Library
Ovarian cancer (OC) is the leading cause of death in patients with gynecologic cancers. Due
to late diagnosis and resistance to chemotherapy, the 5‐year survival rate in patients with …

lncRNA UCA1 mediates resistance to cisplatin by regulating the miR-143/FOSL2-signaling pathway in ovarian cancer

Z Li, H Niu, Q Qin, S Yang, Q Wang, C Yu, Z Wei… - … Therapy-Nucleic Acids, 2019 - cell.com
The aim of this study was to explore the roles of the long noncoding RNA (lncRNA) urothelial
carcinoma-associated 1 (UCA1) on cisplatin resistance in ovarian cancer and the underlying …

UCA1 functions as a competing endogenous RNA to suppress epithelial ovarian cancer metastasis

Y Yang, Y Jiang, Y Wan, L Zhang, J Qiu, S Zhou… - Tumor Biology, 2016 - Springer
Abstract Urothelial cancer associated 1 (UCA1) is an example of functional long noncoding
RNAs involved in many biologic processes. However, little is known about the association …

[HTML][HTML] UCA1 long non-coding RNA: An update on its roles in malignant behavior of cancers

S Ghafouri-Fard, M Taheri - Biomedicine & Pharmacotherapy, 2019 - Elsevier
The lncRNA urothelial carcinoma-associated 1 (UCA1) is a 1.4 kb long transcript which has
been firstly recognized in human bladder cancer cell line. Subsequent studies revealed its …

The functional role of long non-coding RNA UCA1 in human multiple cancers: a review study

NF Hosseini, H Manoochehri, SG Khoei… - Current molecular …, 2021 - ingentaconnect.com
In various cancers, high-grade tumor and poor survival rate in patients with upregulated
lncRNAs UCA1 have been confirmed. Urothelial carcinoma associated 1 (UCA1) is an …

UCA1 overexpression predicts clinical outcome of patients with ovarian cancer receiving adjuvant chemotherapy

L Zhang, X Cao, L Zhang, X Zhang, H Sheng… - Cancer chemotherapy …, 2016 - Springer
Purpose Urothelial carcinoma associated 1 (UCA1) functions as an oncogene, which
promotes cancer cell proliferation, invasion, and metastasis, and is responsible for drug …

[HTML][HTML] Long non-coding RNA UCA1 promotes retinoblastoma progression by modulating the miR-124/c-myc axis

L Wang, M Wu, X Zhou - American Journal of Translational …, 2022 - ncbi.nlm.nih.gov
The long non-coding RNA (lncRNA), urothelial carcinoma-associated 1 (UCA1), belongs to
cancer-related lncRNAs implicated in various carcinomas, including colorectal and gastric …

The prognostic value and mechanisms of lncRNA UCA1 in human cancer

F Yao, Q Wang, Q Wu - Cancer management and research, 2019 - Taylor & Francis
Long noncoding RNAs (lncRNAs), longer than 200 nucleotides in length, play important
roles in the development and progression of various cancers. An increasing number of …

Circulating lncRNA UCA1 promotes malignancy of colorectal cancer via the miR-143/MYO6 axis

Y Luan, X Li, Y Luan, R Zhao, Y Li, L Liu, Y Hao… - … Therapy-Nucleic Acids, 2020 - cell.com
Exosomes mediate cell-cell crosstalk in cancer progression by transferring a variety of
biomolecules, including long noncoding RNAs (lncRNAs). Long non-coding RNA urothelial …

Downregulation of lncRNA UCA1 inhibits proliferation and invasion of cervical cancer cells through miR-206 expression.

Q Yan, Y Tian, F Hao - Oncology research, 2018 - europepmc.org
Cervical cancer has the second highest incidence rate among cancers in females,
accounting for a majority of cancer-related deaths globally. However, the mechanism of …