[HTML][HTML] The systemic renin-angiotensin system in COVID-19

R Reindl-Schwaighofer, S Hödlmoser, O Domenig… - Scientific Reports, 2022 - nature.com
SARS-CoV-2 gains cell entry via angiotensin-converting enzyme (ACE) 2, a membrane-
bound enzyme of the “alternative”(alt) renin-angiotensin system (RAS). ACE2 counteracts …

[HTML][HTML] Plasmatic renin-angiotensin system in normotensive and hypertensive patients hospitalized with COVID-19

MG Silva, GR Corradi, JIP Duhalde, M Nuñez… - Biomedicine & …, 2022 - Elsevier
Background Besides its counterbalancing role of the renin-angiotensin system (RAS),
angiotensin-converting enzyme (ACE) 2 is the receptor for the type 2 coronavirus that …

A pilot study to assess the circulating renin-angiotensin system in COVID-19 acute respiratory failure

DC Files, KW Gibbs, CL Schaich… - … of Physiology-Lung …, 2021 - journals.physiology.org
The renin-angiotensin system (RAS) is fundamental to COVID-19 pathobiology, due to the
interaction between the SARS-CoV-2 virus and the angiotensin-converting enzyme 2 …

Two hits to the renin‐angiotensin system may play a key role in severe COVID‐19

YH Tseng, RC Yang, TS Lu - The Kaohsiung journal of medical …, 2020 - Wiley Online Library
The spike glycoprotein on the virion surface docking onto the angiotensin‐converting
enzyme (ACE) 2 dimer is an essential step in the process of severe acute respiratory …

Plasma angiotensin peptide profiling and ACE (angiotensin-converting enzyme)-2 activity in COVID-19 patients treated with pharmacological blockers of the renin …

U Kintscher, A Slagman, O Domenig, R Röhle… - …, 2020 - Am Heart Assoc
Results Ang-peptide equilibrium concentrations did not significantly differ between the
control and COVID groups without ACE inhibitor/ARB treatment (Figure [B], left). More …

[HTML][HTML] Plasma angiotensin II is increased in critical coronavirus disease 2019

RL Camargo, B Bombassaro… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) employs angiotensin-
converting enzyme 2 (ACE2) as its receptor for cell entrance, and studies have suggested …

[HTML][HTML] The fight against COVID-19: Striking a balance in the renin–angiotensin system

AQ Dean, WP Bozza, JD Twomey, S Luo, A Nalli… - Drug discovery today, 2021 - Elsevier
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
enters host cells by interacting with membrane-bound angiotensin-converting enzyme 2 …

The prognostic importance of the angiotensin II/angiotensin-(1–7) ratio in patients with SARS-CoV-2 infection

LM Amezcua-Guerra, L Del Valle… - Therapeutic …, 2022 - journals.sagepub.com
Background: Information about angiotensin II (Ang II), angiotensin-converting enzyme 2
(ACE2), and Ang-(1–7) levels in patients with COVID-19 is scarce. Objective: To …

High rate of increased level of plasma Angiotensin II and its gender difference in COVID-19: an analysis of 55 hospitalized patients with COVID-19 in a single hospital …

N Liu, Y Hong, RG Chen, HM Zhu - medRxiv, 2020 - medrxiv.org
Background 2019 Novel coronavirus disease (COVID-19) is turning into a pandemic
globally lately. Angiotensin-converting enzyme 2 (ACE2) is identified as an important …

[HTML][HTML] The impact of angiotensin-converting enzyme-2/angiotensin 1-7 Axis in establishing severe COVID-19 consequences

MA Maranduca, DM Tanase, CT Cozma, N Dima… - Pharmaceutics, 2022 - mdpi.com
The COVID-19 pandemic has put a tremendous stress on the medical community over the
last two years. Managing the infection proved a lot more difficult after several research …