Crosstalk between the gut microbiota and epithelial cells under physiological and infectious conditions

A Zhou, Y Yuan, M Yang, Y Huang, X Li, S Li… - Frontiers in Cellular …, 2022 - frontiersin.org
The gastrointestinal tract (GIT) is considered the largest immunological organ, with a diverse
gut microbiota, that contributes to combatting pathogens and maintaining human health …

Roles of intestinal epithelial cells in the maintenance of gut homeostasis

R Okumura, K Takeda - Experimental & molecular medicine, 2017 - nature.com
The intestine is a unique organ inhabited by a tremendous number of microorganisms.
Intestinal epithelial cells greatly contribute to the maintenance of the symbiotic relationship …

Current understanding of the gut microbiota shaping mechanisms

CS Chang, CY Kao - Journal of biomedical science, 2019 - Springer
Increasing evidences have shown strong associations between gut microbiota and many
human diseases, and understanding the dynamic crosstalks of host-microbe interaction in …

Microbial metabolites determine host health and the status of some diseases

P Sittipo, J Shim, YK Lee - International journal of molecular sciences, 2019 - mdpi.com
The gastrointestinal (GI) tract is a highly complex organ composed of the intestinal
epithelium layer, intestinal microbiota, and local immune system. Intestinal microbiota …

The role of the gut microbiome and its metabolites in metabolic diseases

J Wu, K Wang, X Wang, Y Pang, C Jiang - Protein & cell, 2021 - academic.oup.com
It is well known that an unhealthy lifestyle is a major risk factor for metabolic diseases, while
in recent years, accumulating evidence has demonstrated that the gut microbiome and its …

Gut microbiota: an integral moderator in health and disease

Q Feng, WD Chen, YD Wang - Frontiers in microbiology, 2018 - frontiersin.org
The gut microbiota, as the main member in gut microecology, is an essential mediator in
health and disease. The gut microbiota interacts with various organs and systems in the …

New insights into therapeutic strategies for gut microbiota modulation in inflammatory diseases

AT Vieira, C Fukumori… - Clinical & translational …, 2016 - Wiley Online Library
The interaction between the gut microbiota and the host immune system is very important for
balancing and resolving inflammation. The human microbiota begins to form during …

Interaction between the gut microbiome and mucosal immune system

N Shi, N Li, X Duan, H Niu - Military Medical Research, 2017 - Springer
The gut microbiota, the largest symbiotic ecosystem with the host, has been shown to play
important roles in maintaining intestinal homeostasis. Dysbiosis of the gut microbiome is …

Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis

N Ma, X Chen, LJ Johnston, X Ma - Imeta, 2022 - Wiley Online Library
Intestinal epithelium undergoes rapid cellular turnover, relying on the local niche, to support
intestinal stem cells (ISCs) function and self‐renewal. Research into the association …

Human gut microbiota in health and disease: Unveiling the relationship

M Afzaal, F Saeed, YA Shah, M Hussain… - Frontiers in …, 2022 - frontiersin.org
The human gut possesses millions of microbes that define a complex microbial community.
The gut microbiota has been characterized as a vital organ forming its multidirectional …