[HTML][HTML] Mathematical model predicts response to chemotherapy in advanced non-resectable non-small cell lung cancer patients treated with platinum-based doublet
E Kozłowska, R Suwiński, M Giglok… - PLoS Computational …, 2020 - journals.plos.org
We developed a computational platform including machine learning and a mechanistic
mathematical model to find the optimal protocol for administration of platinum-doublet …
mathematical model to find the optimal protocol for administration of platinum-doublet …
[HTML][HTML] In Silico Oncology: Quantification of the In Vivo Antitumor Efficacy of Cisplatin-Based Doublet Therapy in Non-Small Cell Lung Cancer (NSCLC) through a …
E Kolokotroni, D Dionysiou, C Veith… - PLoS Computational …, 2016 - journals.plos.org
The 5-year survival of non-small cell lung cancer patients can be as low as 1% in advanced
stages. For patients with resectable disease, the successful choice of preoperative …
stages. For patients with resectable disease, the successful choice of preoperative …
Pharmacokinetic/pharmacodynamic modeling of combination-chemotherapy for lung cancer
LT Curtis, VH van Berkel, HB Frieboes - Journal of theoretical biology, 2018 - Elsevier
Chemotherapy for non-small cell lung cancer (NSCLC) typically involves a doublet regimen
for a number of cycles. For any particular patient, a course of treatment is usually chosen …
for a number of cycles. For any particular patient, a course of treatment is usually chosen …
[HTML][HTML] Prediction of treatment response for combined chemo-and radiation therapy for non-small cell lung cancer patients using a bio-mathematical model
The goal of this work was to develop a mathematical model to predict Kaplan–Meier survival
curves for chemotherapy combined with radiation in Non-Small Cell Lung Cancer patients …
curves for chemotherapy combined with radiation in Non-Small Cell Lung Cancer patients …
[HTML][HTML] How mathematical modeling could contribute to the quantification of metastatic tumor burden under therapy: insights in immunotherapeutic treatment of non …
Background Cancer is one of the leading death causes globally with about 8.2 million
deaths per year and an increase in numbers in recent years. About 90% of cancer deaths do …
deaths per year and an increase in numbers in recent years. About 90% of cancer deaths do …
[HTML][HTML] Development and validation of a decision model for the evaluation of novel lung cancer treatments in the Netherlands
ZA Mfumbilwa, JA Wilschut, MJHG Simons… - Scientific reports, 2023 - nature.com
Recent discoveries in molecular diagnostics and drug treatments have improved the
treatment of patients with advanced (inoperable) non-squamous non-small cell lung cancer …
treatment of patients with advanced (inoperable) non-squamous non-small cell lung cancer …
Predicting efficacy assessment of combined treatment of radiotherapy and nivolumab for NSCLC patients through virtual clinical trials using QSP modeling
M Schirru, H Charef, KE Ismaili, F Fenneteau… - … of Pharmacokinetics and …, 2024 - Springer
Abstract Non-Small Cell Lung Cancer (NSCLC) remains one of the main causes of cancer
death worldwide. In the urge of finding an effective approach to treat cancer, enormous …
death worldwide. In the urge of finding an effective approach to treat cancer, enormous …
Modeling of combination chemotherapy and immunotherapy for lung cancer
LT Curtis, HB Frieboes - … Conference of the IEEE Engineering in …, 2019 - ieeexplore.ieee.org
Cancer has traditionally been studied from a basic science perspective, focusing on the
underlying biology, physiology, and biochemistry. Engineering has supplemented this effort …
underlying biology, physiology, and biochemistry. Engineering has supplemented this effort …
[HTML][HTML] A clinical prognostic score to predict survival of advanced or metastatic non-small cell lung cancer (NSCLC) patients receiving first-line chemotherapy: a …
J Gong, L Xu, Z Li, X Hu, J Liu, Y Teng… - … Medical Journal of …, 2018 - ncbi.nlm.nih.gov
A Clinical Prognostic Score to Predict Survival of Advanced or Metastatic Non-Small Cell Lung
Cancer (NSCLC) Patients Receiving First-Line Chemotherapy: A Retrospective Analysis …
Cancer (NSCLC) Patients Receiving First-Line Chemotherapy: A Retrospective Analysis …
A prediction model for early death in non-small cell lung cancer patients following curative-intent chemoradiotherapy
A Jochems, I El-Naqa, M Kessler, CS Mayo… - Acta …, 2018 - Taylor & Francis
Background: Early death after a treatment can be seen as a therapeutic failure. Accurate
prediction of patients at risk for early mortality is crucial to avoid unnecessary harm and …
prediction of patients at risk for early mortality is crucial to avoid unnecessary harm and …