Background Genotype imputation is an important procedure in current genomic analysis such as genome-wide association studies, meta-analyses and fine mapping. Although high …
K Stahl, D Gola, IR König - Frontiers in genetics, 2021 - frontiersin.org
Despite the widespread use of genotype imputation tools and the availability of different approaches, late developments of currently used programs have not been compared …
Well-powered genomic studies require genome-wide marker coverage across many individuals. For non-model species with few genomic resources, high-throughput …
Genotype imputation is an important tool in human genetics studies, which uses reference sets with known genotypes and prior knowledge on linkage disequilibrium and …
We address the task of genotype imputation to a dense reference panel given genotype likelihoods computed from ultralow coverage sequencing as inputs. In this setting, the data …
Genotype imputation is a key step in the analysis of genome-wide association studies. Upcoming very large reference panels, such as those from The 1000 Genomes Project and …
P Lin, SM Hartz, Z Zhang, SF Saccone, J Wang… - PloS one, 2010 - journals.plos.org
Background As the amount of data from genome wide association studies grows dramatically, many interesting scientific questions require imputation to combine or expand …
Genotype imputation is now commonly performed following genome-wide genotyping experiments. Imputation increases the density of analyzed genotypes in the dataset …
Background Genome imputation, admixture resolution and genome-wide association analyses are timely and computationally intensive processes with many composite and …