Calcium signaling pathway is involved in the shedding of ACE2 catalytic ectodomain: new insights for clinical and therapeutic applications of ACE2 for COVID-19
A García-Escobar, S Vera-Vera, A Jurado-Román… - Biomolecules, 2022 - mdpi.com
The angiotensin-converting enzyme 2 (ACE2) is a type I integral membrane that exists in two
forms: the first is a transmembrane protein; the second is a soluble catalytic ectodomain of …
forms: the first is a transmembrane protein; the second is a soluble catalytic ectodomain of …
The soluble catalytic ectodomain of ACE2 a biomarker of cardiac remodelling: new insights for heart failure and COVID19
A Garcia-Escobar, S Jimenez-Valero, G Galeote… - Heart Failure …, 2021 - Springer
The angiotensin-converting enzyme 2 (ACE2) is a type I integral membrane that was
discovered two decades ago. The ACE2 exists as a transmembrane protein and as a …
discovered two decades ago. The ACE2 exists as a transmembrane protein and as a …
ACE2 as a therapeutic target for COVID-19; its role in infectious processes and regulation by modulators of the RAAS system
V Michaud, M Deodhar, M Arwood… - Journal of Clinical …, 2020 - mdpi.com
Angiotensin converting enzyme 2 (ACE2) is the recognized host cell receptor responsible for
mediating infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
mediating infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
[HTML][HTML] ACE2 in the era of SARS-CoV-2: controversies and novel perspectives
F Saponaro, G Rutigliano, S Sestito… - Frontiers in Molecular …, 2020 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …
Targeting ACE2 for COVID-19 therapy: opportunities and challenges
The coronavirus disease (COVID-19) pandemic is sweeping the globe. Even with a number
of effective vaccines being approved and available to the public, new cases and escalating …
of effective vaccines being approved and available to the public, new cases and escalating …
Angiotensin converting enzyme 2: a double-edged sword
A, ACE2 balances the 2 axes of the RAS, increased ACE2 promotes the protective
ACE2/angiotensin 1–7 (Ang 1–7)/Mas receptor axis (MASR), and loss of ACE2 results in a …
ACE2/angiotensin 1–7 (Ang 1–7)/Mas receptor axis (MASR), and loss of ACE2 results in a …
[HTML][HTML] Induced dysregulation of ACE2 by SARS-CoV-2 plays a key role in COVID-19 severity
ME Mehrabadi, R Hemmati, A Tashakor… - Biomedicine & …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of COVID-19, is
reported to increase the rate of mortality worldwide. COVID-19 is associated with acute …
reported to increase the rate of mortality worldwide. COVID-19 is associated with acute …
ACE2: its potential role and regulation in severe acute respiratory syndrome and COVID‐19
COVID‐19, a new disease caused by the 2019‐novel coronavirus (SARS‐CoV‐2), has
swept the world and challenged its culture, economy, and health infrastructure. Forced …
swept the world and challenged its culture, economy, and health infrastructure. Forced …
Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences
Coronavirus disease 2019 (COVID-19) causes persistent endothelial inflammation, lung,
cardiovascular, kidney and neurological complications, and thromboembolic phenomena of …
cardiovascular, kidney and neurological complications, and thromboembolic phenomena of …
[HTML][HTML] ACE2 as drug target of COVID-19 virus treatment, simplified updated review
G Mostafa-Hedeab - Reports of biochemistry & molecular biology, 2020 - ncbi.nlm.nih.gov
Background: Since its first appearance in December of 2019, regular updates around the
world demonstrates that the number of new Corona Virus 2019 (COVID-19) cases are …
world demonstrates that the number of new Corona Virus 2019 (COVID-19) cases are …