The global prevalence of depression is high during childbearing. Due to the associated risks
to the mother and baby, the selective serotonin reuptake inhibitor fluoxetine (FLX) is often …

Background Stress and anxiety-related behaviors are seen in many organisms. Studies
have shown that in humans and other animals, treatment with selective serotonin reuptake …

Upon binding of cortisol, the glucocorticoid receptor (GR) regulates the transcription of
specific target genes, including those that encode the stress hormones corticotropin …

Zebrafish, Danio rerio, is an emerging model organism in stress and neurobehavioral
studies. In nature, the species forms shoals, yet when kept in pairs it exhibits an agonistic …

Larval zebrafish (Danio rerio) were exposed (96 h) to selective serotonin reuptake inhibitors
(SSRIs) fluoxetine and sertraline and changes in transcriptomes analyzed by Affymetrix …

We investigated the effects of fluoxetine, a selective serotonin reuptake inhibitor, on
neuroendocrine function and the reproductive axis in female goldfish. Fish were given …

Fluoxetine (FLX) is a pharmaceutical acting as a selective serotonin reuptake inhibitor and is
used to treat depression in humans. Fluoxetine and the major active metabolite …

Selective serotonin reuptake inhibitors (SSRIs) have been shown to interfere with various
physiological functions of aquatic organisms, yet the neuroactive potential of low …

Fluoxetine is one of the most prescribed psychotropic medications, and is an agent of
increasing interest for environmental toxicology. Fish and other aquatic organisms are …

In zebrafish (Danio rerio), de novo synthesis of cortisol in response to stressor exposure
commences only after hatch. Maternally deposited cortisol is present during embryogenesis …