Only a very small fraction of long noncoding RNAs (lncRNAs) are well characterized. The evolutionary history of lncRNAs can provide insights into their functionality, but the absence …
P Grote, BG Herrmann - Trends in Genetics, 2015 - cell.com
A large proportion of the cellular transcriptome of higher vertebrates consists of non-protein coding transcripts, among them the long noncoding RNAs (lncRNAs). Although lncRNAs are …
Mammalian genomes are pervasively transcribed, to produce thousands of long non-coding RNAs (lncRNAs),. A few of these lncRNAs have been shown to recruit regulatory complexes …
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally uncharacterized. Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we …
F Constanty, A Shkumatava - Development, 2021 - journals.biologists.com
The number of long noncoding RNAs (lncRNAs) with characterized developmental and cellular functions continues to increase, but our understanding of the molecular mechanisms …
I Grammatikakis, A Lal - Mammalian Genome, 2022 - Springer
Long noncoding RNAs (lncRNAs) have emerged as regulators of diverse cellular processes. Although the vast majority of lncRNAs are expressed at lower levels compared to …
Whole genome transcriptomic analyses have identified large numbers of dynamically expressed long non-protein-coding RNAs (lncRNAs) in mammals and other animals whose …
A large proportion of functional sequence within mammalian genomes falls outside protein- coding exons and can be transcribed into long RNAs. However, the roles in mammalian …
Over the last decade, the increasing interest in long non-coding RNAs (lncRNAs) has led to the discovery of these transcripts in multiple organisms. LncRNAs tend to be specifically …