Background. Infection caused by SARS-CoV-2 mostly affects the upper and lower
respiratory tracts and causes symptoms ranging from the common cold to pneumonia with …

This study is a successor of our previous work concerning changes in the chemokine profile
in infection that are associated with different SARS-CoV-2 genetic variants. The goal of our …

Patients immune phenotype/genotype data may be useful to understand the molecular
mechanisms involved in SARS-CoV-2 infection and can contribute to the identify the …

The exact pathophysiology of severe COVID-19 is not entirely elucidated, but it has been
established that hyperinflammatory responses and cytokine storms play important roles. The …

Abstract Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We investigated the …

Background Chemokine levels in severe coronavirus disease 2019 (COVID-19) patients
have been shown to be markedly elevated. But the role of chemokines in mild COVID-19 …

Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

The chemokine receptor CCR5 has been implicated in COVID-19. CCR5 and its ligands are
overexpressed in patients. The pharmacological targeting of CCR5 would improve the …

Immune dysregulation is a key feature of the coronavirus disease-2019 (COVID-19).
However, disparities in responses across ethnic groups are underappreciated. This study …

Objectives Cytokine dysregulation has been proposed as one of the main culprits for severe
COVID-19 and poor prognosis. We examined the parallel presence of lymphopoietic …