The binary classification of chronic diseases

Z Elkoshi - Journal of Inflammation Research, 2019 - Taylor & Francis
Acute diseases start with an insult and end when insult disappears. If the trauma induces an
immune reaction (which happens in most cases), this reaction must be terminated with some …

Infections and autoimmunity: a panorama

V Pordeus, M Szyper-Kravitz, RA Levy, NM Vaz… - Clinical reviews in …, 2008 - Springer
Abstract For more than 2,000 years, it was thought that malignant spirits caused diseases.
By the end of nineteenth century, these beliefs were displaced by more modern concepts of …

“High Treg” inflammations promote (most) non-hematologic cancers while “Low Treg” inflammations promote lymphoid cancers

Z Elkoshi - Journal of Inflammation Research, 2020 - Taylor & Francis
In an earlier publication, a binary classification of chronic diseases has been proposed.
Chronic diseases were classified as “high Treg” or “low Treg” diseases depending on …

Multiple associations between a broad spectrum of autoimmune diseases, chronic inflammatory diseases and cancer

AL Franks, JE Slansky - Anticancer research, 2012 - ar.iiarjournals.org
Background: Many recent studies suggest the immune system plays a significant role in the
pathogenesis of autoimmune diseases, chronic inflammatory diseases, and cancer …

Infections and autoimmunity–new insights into an age-old reciprocity

Y Segal, D Zohar, Y Shoenfeld - Current Opinion in Rheumatology, 2018 - journals.lww.com
The development of autoimmunity is a complex process, shaped by various factors, both
genetic and environmental, composing what is commonly referred to as 'the mosaic of …

Infections and autoimmunity: the multifaceted relationship

P Sfriso, A Ghirardello, C Botsios… - Journal of leukocyte …, 2010 - academic.oup.com
The relationship between infections and autoimmunity as well as the risk of infections due to
antirheumatic agents, including corticosteroids, immunosuppressants and biologics, are …

[PDF][PDF] Inflammation: chronic

D Wakefield, RK Kumar - Encyclopedia of life sciences (ELS), 2001 - researchgate.net
Chronic inflammation may result from failure to eliminate an acute inflammatory irritant, from
an autoimmune response to a self antigen, or may be caused by an innately chronic irritant …

Pathogen infection and autoimmune disease

U Christen - Clinical & Experimental Immunology, 2019 - academic.oup.com
For many readers, the title 'pathogen infection and autoimmune disease'might suggest that
pathogens are the suspected drivers of autoimmune disease. This, of course, is a perfectly …

Infection, immunoregulation, and cancer

GAW Rook, A Dalgleish - Immunological reviews, 2011 - Wiley Online Library
As man has moved rapidly from the hunter–gatherer environment to the living conditions of
the industrialized countries, the incidences of some cancers have increased alarmingly …

Pathogen infection and autoimmunity

U Christen - International reviews of immunology, 2014 - Taylor & Francis
Autoimmune diseases are an ever-growing problem for patients as well as for the economy.
It has been estimated that 5–10% of the general population suffer from any kind of …