Advanced phenotyping of cardiovascular diseases has evolved with the application of high-
resolution omics screening to populations enrolled in large-scale observational and clinical …

Precision medicine strives to delineate disease using multiple data sources—from genomics
to digital health metrics—in order to be more precise and accurate in our diagnoses …

Cardiovascular diseases are the leading cause of death around the world. Despite the
larger number of genes and loci identified, the precise mechanisms by which these genes …

The complex landscape of cardiovascular diseases encompasses a wide range of related
pathologies arising from diverse molecular mechanisms and exhibiting heterogeneous …

The ability to generate multi-omics data coupled with deeply characterizing the clinical
phenotype of individual patients promises to improve understanding of complex …

Precision medicine is an integrative approach to cardiovascular disease prevention and
treatment that considers an individual's genetics, lifestyle, and exposures as determinants of …

Cardiovascular diseases (CVD) are the leading cause of death worldwide and display
complex phenotypic heterogeneity caused by many convergent processes, including …

Polygenic diseases, which are genetic disorders caused by the combined action of multiple
genes, pose unique and significant challenges for the diagnosis and management of …

Early identification of coronary atherosclerotic pathogenic mechanisms is useful for
predicting the risk of coronary heart disease (CHD) and future cardiac events. Epigenome …

The traditional paradigm of cardiovascular disease research derives insight from large-
scale, broadly inclusive clinical studies of well-characterized pathologies. These insights are …