[HTML][HTML] Individualized medicine in Africa: bringing the practice into the realms of population heterogeneity

AA Hussein, R Hamad, MJ Newport… - Frontiers in Genetics, 2022 - frontiersin.org
The declared aim of “personalized”,“stratified” or “precision” approaches is to place
individual variation, as ascertained through genomic and various other biomarkers, at the …

H3Africa: current perspectives

N Mulder, A Abimiku, SN Adebamowo… - Pharmacogenomics …, 2018 - Taylor & Francis
Precision medicine is being enabled in high-income countries by the growing availability of
health data, increasing knowledge of the genetic determinants of disease and variation in …

Development to enable precision medicine in Africa

N Mulder - Personalized Medicine, 2017 - Future Medicine
Precision medicine enables the customization of patient care driven by experimental data
and knowledge about an individual or a population. Though the data can include omics data …

[HTML][HTML] Personalizing medicine in Africa: current state, progress and challenges

P Owolabi, Y Adam, E Adebiyi - Frontiers in Genetics, 2023 - frontiersin.org
Personalized medicine has been identified as a powerful tool for addressing the myriad of
health issues facing different health systems globally. Although recent studies have …

Has translational genomics come of age in Africa?

M Kamp, A Krause, M Ramsay - Human Molecular Genetics, 2021 - academic.oup.com
The rapid increase in genomics research in Africa and the growing promise of precision
public health (PPH) begs the question of whether African genomics has come of age and is …

[PDF][PDF] Effective size and effectiveness: next generation sequencing and the practice of genomics in Africa

M Ibrahim, M Musa - Next Generat Sequenc & Applic S, 2016 - researchgate.net
The tremendous and unprecedented insights provided by next generation sequencing into
genome functions, variations and interactions promises an enormous shift in our attitude …

[PDF][PDF] Conference report: First Pharmacogenetics and Precision Medicine Conference in Africa (April 7–9, 2016, Cape Town, South Africa)

C Dandara, G Suarez-Kurtz… - OMICS: A Journal of …, 2016 - researchgate.net
Africa, the second most populous continent, is home to the most genetically diverse people
on earth with at least 3000 distinct ethnic groups and more than 2000 languages …

African genetic diversity and adaptation inform a precision medicine agenda

L Pereira, L Mutesa, P Tindana, M Ramsay - Nature Reviews Genetics, 2021 - nature.com
The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

Advancing disease genomics beyond COVID-19 and reducing health disparities: what does the future hold for Africa?

C Ibe, AA Otu, NP Mnyambwa - Briefings in Functional …, 2023 - academic.oup.com
The COVID-19 pandemic has ushered in high-throughput sequencing technology as an
essential public health tool. Scaling up and operationalizing genomics in Africa is crucial as …

The opportunity in African genome resource for precision medicine

S Fatumo - EBioMedicine, 2020 - thelancet.com
There is a critical need to increase and diversify genomic study in the global efforts to
achieving full implementation of precision medicine. Given this central importance of Africa …