Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Context New approaches are needed to address the evolution of the primary aldosteronism
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Primary aldosteronism is a frequent cause of secondary hypertension requiring a specific
pharmacological treatment with mineralocorticoid receptor antagonist or with unilateral …

Primary aldosteronism used to be considered a rare cause of secondary hypertension.
However, accruing evidence indicates that primary aldosteronism is more common than …

It is now widely recognized that primary aldosteronism (PA) is much more common than
previously thought, accounting for up to 5–10% of hypertensives, and that aldosterone …

Background Primary aldosteronism is much more common than previously held; it implies
an excessive organ damage to the heart, vessels and kidney, which translates into an …

In the 60 years that have passed since the discovery of the mineralocorticoid hormone
aldosterone, much has been learned about its synthesis (both adrenal and extra-adrenal) …

Primary aldosteronism is the most common single cause of hypertension and is potentially
curable when only one adrenal gland is the culprit. The importance of primary aldosteronism …

Primary aldosteronism involves more than 11% of hypertensive patients who are referred to
specialized centers for the diagnosis and treatment of hypertension. If not diagnosed early it …