The adherence and emigration of leukocytes have been implicated as a rate-limiting step in
the microvascular dysfunction associated with reperfusion of ischemic tissues. The objective …

Intravital microscopic studies of the mesenteric microcirculation have demonstrated that
leukocyte adherence and emigration in postcapillary venules are a characteristic feature of …

Polymorphonuclear leukocytes are known to accumulate in tissues subjected to ischemia
and reperfusion. Studies on endothelial cell monolayers suggest that limited release of …

The objective of this study was to define the role of oxidants and lipid mediators in the
leukocyte-endothelial cell adhesion and albumin leakage elicited in rat mesenteric venules …

BACKGROUND.: Leukocytes are suggested to modulate ischemia/reperfusion injury via
membrane receptor-controlled interaction with the microvascular endothelium. METHODS …

The recruitment of leukocytes into postcapillary venules following reperfusion of ischemic
tissues is a classical inflammatory response that is influenced by a balance of adhesive and …

Previous studies utilizing monoclonal antibodies directed against specific leukocyte-
endothelial cell adhesion proteins have suggested that neutrophils mediate endothelial cell …

Tissue injury resulting from ischemia and reperfusion forms the basis of several important
disorders including myocardial infarction, stroke, and circulatory shock. To examine the role …

Reperfusion of ischemic tissues results in development of a proinflammatory,
prothrombogenic phenotype, culminating in the recruitment of leukocytes and platelets …

OBJECTIVES The expression of endothelial adhesion molecules and their functional
significance in leukocyte adhesion to human myocardial blood vessels in acute myocardial …