Angiotensin II (ANG II) has been etiologically linked to vascular disease; however, its role in
the alterations of endothelial function that occur in vascular disorders is not completely …

Abstract Aims Matrix metalloproteinases (MMPs) have been implicated in the development
of hypertension in animal models and humans. Mmp2 deletion did not change Ang II …

Although accumulating lines of evidence indicate the proangiogenic role of angiotensin II
(Ang II), little is known about the molecular mechanisms associated with such an effect. This …

Abstract Angiotensin II (Ang II)-mediated hypertension increases the risk for acute coronary
syndrome, a consequence of atherosclerotic plaque rupture, which may be caused by matrix …

Increased levels of angiotensin II (Ang II) and activated matrix metalloproteinase 2 (MMP-2)
produced by human aortic smooth muscle cells (human ASMCs) have recently been …

The renin-angiotensin system contributes to atherogenesis. Matrix metalloproteinases
(MMP) are thought to participate in plaque destabilization through degradation of …

Angiotensin II (AngII) is widely recognized as a critical regulator of the development of
atherosclerosis. Matrix metalloproteinases (MMPs) are thought to participate in plaque …

We examined whether ANG II and TNF-α cooperatively induce vascular inflammation using
the expression of monocyte chemoattractant protein (MCP)-1 as a marker of vascular …

Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in tissue
remodeling processes. TIMP-1 is the main native inhibitor of MMPs and it contributes to the …

Angiotensin II (Ang II) is associated with vascular hypertrophy, endothelial dysfunction and
activation of a number of inflammatory molecules, however the linear events involved in the …