Dendritic calcium signaling is central to neural plasticity mechanisms that allow animals to
adapt to the environment. Intracellular calcium release (ICR) from the endoplasmic reticulum …

The dendritic arbors of neurons are organized into unique spatial patterns that are well
suited for their specific functions. Although the intracellular signaling pathways that …

Feature-selective firing allows networks to produce representations of the external and
internal environments. Despite its importance, the mechanisms generating neuronal feature …

The ability to record transient cellular events in the DNA or RNA of cells would enable
precise, large-scale analysis, selection, and reprogramming of heterogeneous cell …

In layer 2/3 pyramidal neurons of barrel cortex in vivo, calcium ion concentration ([Ca 2+])
transients in apical dendrites evoked by sodium action potentials are limited to regions close …

Experience-dependent changes in behavior are mediated by long-term functional
modifications in brain circuits. Activity-dependent plasticity of synaptic input is a major …

Neural pathways projecting from sensory organs to higher brain centers form topographic
maps in which neighbor relationships are preserved from a sending to a receiving neural …

Transforming synaptic input into action potential output is a fundamental function of neurons.
The pattern of action potential output from principal cells of the mammalian hippocampus …

Back-propagating action potentials (bAPs) regulate synaptic plasticity by evoking voltage-
dependent calcium influx throughout dendrites. Attenuation of bAP amplitude in distal …

Synaptic inputs on dendrites are nonlinearly converted to action potential outputs, yet the
spatiotemporal patterns of dendritic activation remain to be elucidated at single-synapse …