CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement

C Li, E Brant, H Budak, B Zhang - Journal of Zhejiang University-SCIENCE …, 2021 - Springer
Since it was first recognized in bacteria and archaea as a mechanism for innate viral
immunity in the early 2010s, clustered regularly interspaced short palindromic repeats …

CRISPR-based genome editing tools: Insights into technological breakthroughs and future challenges

M Mushtaq, A Ahmad Dar, M Skalicky, A Tyagi… - Genes, 2021 - mdpi.com
Genome-editing (GE) is having a tremendous influence around the globe in the life science
community. Among its versatile uses, the desired modifications of genes, and more …

Applications of CRISPR–Cas in agriculture and plant biotechnology

H Zhu, C Li, C Gao - Nature Reviews Molecular Cell Biology, 2020 - nature.com
The prokaryote-derived CRISPR–Cas genome editing technology has altered plant
molecular biology beyond all expectations. Characterized by robustness and high target …

A technological and regulatory outlook on CRISPR crop editing

R Globus, U Qimron - Journal of cellular biochemistry, 2018 - Wiley Online Library
Generating plants with increased yields while maintaining low production and maintenance
costs is highly important since plants are the major food source for humans and animals, as …

Gene editing and crop improvement using CRISPR-Cas9 system

L Arora, A Narula - Frontiers in plant science, 2017 - frontiersin.org
Advancements in Genome editing technologies have revolutionized the fields of functional
genomics and crop improvement. CRISPR/Cas9 (clustered regularly interspaced short …

Targeted gene manipulation in plants using the CRISPR/Cas technology

D Zhang, Z Li, JF Li - Journal of Genetics and Genomics, 2016 - Elsevier
The CRISPR/Cas technology is emerging as a revolutionary genome editing tool in diverse
organisms including plants, and has quickly evolved into a suite of versatile tools for …

The CRISPR–Cas system for plant genome editing: advances and opportunities

V Kumar, M Jain - Journal of experimental botany, 2015 - academic.oup.com
Genome editing is an approach in which a specific target DNA sequence of the genome is
altered by adding, removing, or replacing DNA bases. Artificially engineered hybrid …

CRISPR technology: A decade of genome editing is only the beginning

JY Wang, JA Doudna - Science, 2023 - science.org
The advent of clustered regularly interspaced short palindromic repeat (CRISPR) genome
editing, coupled with advances in computing and imaging capabilities, has initiated a new …

Exploring the potential of CRISPR/Cas genome editing for vegetable crop improvement: An overview of challenges and approaches

T Das, U Anand, T Pal, S Mandal… - Biotechnology and …, 2023 - Wiley Online Library
Vegetables provide many nutrients in the form of fiber, vitamins, and minerals, which make
them an important part of our diet. Numerous biotic and abiotic stresses can affect crop …

Compendium of plant-specific CRISPR vectors and their technical advantages

A Alok, H Chauhan, SK Upadhyay, A Pandey, J Kumar… - Life, 2021 - mdpi.com
CRISPR/Cas mediated genome editing is a revolutionary approach for manipulating the
plant genome. However, the success of this technology is highly dependent on selection of a …