Cells expressing Toll-like receptor (TLR), TLR2 in association with TLR1, TLR6 or some other unknown co-receptor can respond upon interaction with a large variety of microbial …
T Kawai, S Akira - Cell Death & Differentiation, 2006 - nature.com
The Toll-like receptor (TLR) family plays an instructive role in innate immune responses against microbial pathogens, as well as the subsequent induction of adaptive immune …
K Takeda, S Akira - Current protocols in immunology, 2015 - Wiley Online Library
The mammalian Toll‐like receptor (TLR) family consists of 13 members, and recognizes specific patterns of microbial components, called pathogen‐associated molecular patterns …
J Yang, H Yan - Cellular & molecular immunology, 2017 - nature.com
The innate immune system plays an essential role in the host defense against infections by initially sensing and recognizing diverse microbial pathogens and directing adaptive …
M Molteni, S Gemma, C Rossetti - Mediators of inflammation, 2016 - Wiley Online Library
Toll‐like receptor 4 (TLR4) belongs to the family of pattern recognition receptors (PRRs). They are highly conserved receptors that recognize conserved pathogen‐associated …
E Vercammen, J Staal, R Beyaert - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Toll-like receptors (TLRs) form a major group of transmembrane receptors that are involved in the detection of invading pathogens. Double-stranded RNA is a marker for viral infection …
During an infection, one of the principal challenges for the host is to detect the pathogen and activate a rapid defensive response. The Toll-like family of receptors (TLRs), among other …
The innate immune system is the primary line of defence against invading pathogenic microbes. Toll‐like receptors (TLRs) are a family of membrane receptors which play a pivotal …
D Xu, H Liu, M Komai-Koma - Cell Mol Immunol, 2004 - researchgate.net
Toll-like receptors (TLR) are pathogen-associated molecular patterns (PAMPs) recognition receptors that play an important role in protective immunity against infection and …