Endothelial dysfunction and inflammation: immunity in rheumatoid arthritis

XZ Yang, Y Chang, W Wei - Mediators of inflammation, 2016 - Wiley Online Library
Inflammation, as a feature of rheumatoid arthritis (RA), leads to the activation of endothelial
cells (ECs). Activated ECs induce atherosclerosis through an increased expression of …

Mechanisms of endothelial dysfunction in rheumatoid arthritis: lessons from animal studies

P Totoson, K Maguin-Gaté, C Prati, D Wendling… - Arthritis research & …, 2014 - Springer
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by
articular and extra-articular manifestations involving cardiovascular diseases (CVDs), which …

Endothelial dysfunction in patients with rheumatoid arthritis: the role of hypertension

P Anyfanti, E Gavriilaki, S Douma… - Current Hypertension …, 2020 - Springer
Abstract Purpose of Review To review the data on the role of endothelial dysfunction and the
impact of hypertension as a potent mediator of cardiovascular disease in patients with …

Microvascular endothelial dysfunction in rheumatoid arthritis

R Bordy, P Totoson, C Prati, C Marie… - Nature Reviews …, 2018 - nature.com
The systemic autoimmune disease rheumatoid arthritis (RA) is characterized by increased
cardiovascular mortality and morbidity and is an independent cardiovascular risk factor …

Rheumatoid arthritis, inflammation, and atherosclerosis

D Hürlimann, F Enseleit, F Ruschitzka - Herz, 2004 - Springer
Patients with rheumatoid arthritis (RA) have a two to five times increased risk of developing
premature cardiovascular disease that shortens life expectancy by 5–10 years. Traditional …

Endothelial dysfunction in rheumatoid arthritis: mechanistic insights and correlation with circulating markers of systemic inflammation

P Totoson, K Maguin-Gaté, M Nappey, D Wendling… - PloS one, 2016 - journals.plos.org
Objectives To determine mechanisms involved in endothelial dysfunction (ED) during the
course of arthritis and to investigate the link between cytokines, chemokines and …

The role of endothelial function and its assessment in rheumatoid arthritis

F Khan, B Galarraga, JJF Belch - Nature Reviews Rheumatology, 2010 - nature.com
Patients with rheumatoid arthritis (RA) have a reduced life expectancy when compared with
the general population, largely attributable to cardiovascular disease. Factors that contribute …

Endothelial dysfunction in chronic inflammatory diseases

CM Steyers III, FJ Miller Jr - International journal of molecular sciences, 2014 - mdpi.com
Chronic inflammatory diseases are associated with accelerated atherosclerosis and
increased risk of cardiovascular diseases (CVD). As the pathogenesis of atherosclerosis is …

Rheumatoid arthritis (RA) and cardiovascular disease.

A Blum, M Adawi - Autoimmunity reviews, 2019 - europepmc.org
Patients with rheumatoid arthritis (RA) suffer cardiovascular events 1.5-2 fold than the
general population, and cardiovascular (CV) events are leading cause of death in patients …

[HTML][HTML] Vascular function and inflammation in rheumatoid arthritis: the role of physical activity

GS Metsios, A Stavropoulos-Kalinoglou… - The open …, 2010 - ncbi.nlm.nih.gov
Inflammation disturbs biochemical pathways involved in homeostasis of the endothelium.
Research has established clear links between inflammatory mediators, particularly C …