[HTML][HTML] Oral antiviral treatments for COVID-19: opportunities and challenges

L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
The use of antiviral COVID-19 medications can successfully inhibit SARS-CoV-2 replication
and prevent disease progression to a more severe form. However, the timing of antiviral …

[HTML][HTML] First-generation oral antivirals against SARS-CoV-2

P Sendi, RR Razonable, SB Nelson, A Soriano… - Clinical Microbiology …, 2022 - Elsevier
Background Oral drugs against severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) have received emergency use authorization for the treatment of mild-to-moderate …

[PDF][PDF] Antiviral agents for the treatment of COVID-19: Progress and challenges

M Singh, E de Wit - Cell Reports Medicine, 2022 - cell.com
The COVID-19 pandemic has seen clinical development and use of antiviral therapies at an
unprecedented speed. Antiviral therapies have greatly improved the clinical outcome in …

[HTML][HTML] Oral antivirals for the prevention and treatment of SARS-CoV-2 infection

V Soriano, C De-Mendoza, B Edagwa, A Treviño… - AIDS …, 2022 - ncbi.nlm.nih.gov
Vaccines and antivirals are the classical weapons deployed to contain, prevent, and treat life-
threatening viral illnesses. Specifically, for SARS-CoV-2 infection, vaccines protect against …

Molnupiravir and nirmatrelvir-ritonavir: oral coronavirus disease 2019 antiviral drugs

LD Saravolatz, S Depcinski… - Clinical Infectious …, 2023 - academic.oup.com
At a crucial time with rapid spread of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) Omicron variant globally, the United States Food and Drug Administration …

Recent progress of antiviral therapy for coronavirus disease 2019

M Zhao, J Zhang, H Li, Z Luo, J Ye, Y Xu… - European journal of …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has become a global public
health crisis, for which antiviral treatments are considered mainstream therapeutic …

[HTML][HTML] Oral antiviral treatment for COVID-19: a comprehensive review on nirmatrelvir/ritonavir

K Akinosoglou, G Schinas, C Gogos - Viruses, 2022 - mdpi.com
Despite the rapid development of efficient and safe vaccines against COVID-19, the need to
confine the pandemic and treat infected individuals on an outpatient basis has led to the …

Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19: a meta-analysis

W Wen, C Chen, J Tang, C Wang, M Zhou… - Annals of …, 2022 - Taylor & Francis
Background The coronavirus disease (COVID-19) epidemic has not been completely
controlled. Although great achievements have been made in COVID-19 research and many …

Current perspective of antiviral strategies against COVID-19

BA Ahidjo, MWC Loe, YL Ng, CK Mok… - ACS infectious …, 2020 - ACS Publications
COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020.
This novel coronavirus disease, caused by the SARS-CoV-2 virus, has resulted in severe …

[HTML][HTML] An overview of the safety, clinical application and antiviral research of the COVID-19 therapeutics

D Wang, Z Li, Y Liu - Journal of infection and public health, 2020 - Elsevier
Since a novel coronavirus pneumonia outbreak in late December 2019, coronavirus disease-
19 (COVID-19) epidemic has gradually spread worldwide, becoming a major public health …