The subgingival microbiome associated with periodontitis in type 2 diabetes mellitus

B Shi, R Lux, P Klokkevold, M Chang… - The ISME …, 2020 - academic.oup.com
Type 2 diabetes mellitus (T2DM) is a systemic disease, predisposing patients to other
inflammatory conditions including periodontitis. The subgingival microbiome, a key player in …

The role of oral microbiome in periodontitis under diabetes mellitus

H Qin, G Li, X Xu, C Zhang, W Zhong, S Xu… - Journal of oral …, 2022 - Taylor & Francis
Periodontitis is among most common human inflammatory diseases and characterized by
destruction of tooth-supporting tissues that will eventually lead to tooth loss. Diabetes …

The microbiome in periodontitis and diabetes

DNA Silva, M Casarin, S Monajemzadeh… - Frontiers in oral …, 2022 - frontiersin.org
Objectives To perform a comprehensive and integrative review of the available literature on
the potential changes in the microbiome of healthy and individuals with diabetes under …

A tale of two risks: smoking, diabetes and the subgingival microbiome

SM Ganesan, V Joshi, M Fellows, SM Dabdoub… - The ISME …, 2017 - academic.oup.com
Although smoking and diabetes have been established as the only two risk factors for
periodontitis, their individual and synergistic impacts on the periodontal microbiome are not …

Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis

B Shi, M Chang, J Martin, M Mitreva, R Lux… - MBio, 2015 - Am Soc Microbiol
The human microbiome influences and reflects the health or disease state of the host.
Periodontitis, a disease affecting about half of American adults, is associated with alterations …

Dysbiosis and alterations in predicted functions of the subgingival microbiome in chronic periodontitis

ME Kirst, EC Li, B Alfant, YY Chi, C Walker… - Applied and …, 2015 - Am Soc Microbiol
Chronic periodontitis is an inflammatory disease of the periodontium affecting nearly 65
million adults in the United States. Changes in subgingival microbiota have long been …

Subgingival biodiversity in subjects with uncontrolled type‐2 diabetes and chronic periodontitis

RCV Casarin, A Barbagallo, T Meulman… - Journal of …, 2013 - Wiley Online Library
Background and Objective: There is a bidirectional relationship between periodontal
disease and type‐2 diabetes mellitus (DM). Inflammatory mediators may negatively affect …

The salivary microbiome of diabetic and non‐diabetic adults with periodontal disease

A Sabharwal, K Ganley… - Journal of …, 2019 - Wiley Online Library
Background A comparison of the salivary microbiome of non‐diabetic and diabetic cohorts
having periodontal health, gingivitis and periodontitis could reveal microbial signatures …

Periodontitis associates with species-specific gene expression of the oral microbiota

D Belstrøm, F Constancias, DI Drautz-Moses… - npj Biofilms and …, 2021 - nature.com
The purpose of the present investigation was to characterize species-specific bacterial
activity of the oral microbiota in periodontitis. We tested the hypotheses that chronic …

Periodontitis and diabetes mellitus co-morbidity: A molecular dialogue

A Luong, AN Tawfik, H Islamoglu, HS Gobriel… - Journal of Oral …, 2021 - Elsevier
Background Type 2 diabetes mellitus (T2DM) and periodontitis are two biologically linked
diseases that often coexist in complex interaction. While periodontitis may lead to insulin …