The global prevalence of diabetes mellitus was estimated to be 463 million people in 2019
and is predicted to rise to 700 million by 2045. The associated financial and societal costs of …

Introduction: Diabetes mellitus is a very common metabolic disorder affecting more than 400
million people worldwide. Currently available treatments permit to manage the disease but …

Overweight and obesity are major problems in today's society, driving the prevalence of
diabetes and its related complications. It is important to understand the molecular …

Diabetes mellitus due to its high prevalence and associated complications is a major
socioeconomic health problem. Diabetes is characterized by multiple macro-and …

Chronic, low-grade systemic inflammation and impaired microvascular function are critical
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …

Diabetes mellitus causes chronic complications primarily affecting the vasculature of various
organs, risking patients for renal failure, vision loss and heart failure. A newly discovered …

There is no cure for diabetic nephropathy and the molecular mechanisms underlying
disease aetiology remain poorly understood. While current paradigms for clinical …

MicroRNAs (miRNAs) are a family of endogenous small noncoding RNA molecules, of 19–
28 nucleotides in length. In humans, up to 3% of all genes are estimated to encode these …

Today's world population is currently faced with a new type of non-transmissible pandemic:
obesity. This lifestyle-related condition is driving the emergence of the diabetes pandemic …

The discovery in mammalian cells of hundreds of small RNA molecules, called microRNAs,
with the potential to modulate the expression of the majority of the protein‐coding genes has …