Crohn's disease (CD), a form of inflammatory bowel disease, has a higher prevalence in
Ashkenazi Jewish than in non-Jewish European populations. To define the role of …

Links that implicate the gastrointestinal system in Parkinson's disease (PD) pathogenesis
and progression have become increasingly common. PD shares several similarities with …

Variants in the leucine-rich repeat kinase-2 (LRRK2) gene are associated with Parkinson's
disease, leprosy, and Crohn's disease, three disorders with inflammation as an important …

The link between the gut and the brain in Parkinson's disease (PD) pathogenesis is currently
a subject of intense research. Indeed, gastrointestinal dysfunction is known as an early …

LRRK2 was previously identified as a defective gene in Parkinson's disease, and it is also
located in a risk region for Crohn's disease. In this study, we aim to determine whether …

Leucine-rich repeat kinase 2 (LRRK2) is linked to various diseases, including Parkinson's
disease, cancer, and leprosy. Data from LRRK2 knockout mice has highlighted a possible …

The LRRK2/MUC19 gene region constitutes a high-risk genetic locus for the occurrence of
both inflammatory bowel diseases (IBDs) and Parkinson's disease. We show that dendritic …

Sequence variants at or near the leucine-rich repeat kinase 2 (LRRK2) locus have been
associated with susceptibility to three human conditions: Parkinson's disease (PD), Crohn's …

For more than a decade, researchers have sought to uncover the biological function of the
enigmatic leucine rich repeat kinase 2 (LRRK2) enzyme, a large multi-domain protein with …

Inflammatory bowel disease and Parkinson's disease are chronic progressive disorders that
mainly affect different organs: the gut and brain, respectively. Accumulating evidence has …