Background As a leading cause of chronic kidney disease, clinical demand for noninvasive
biomarkers of diabetic kidney disease (DKD) beyond proteinuria is increasing …

Diabetic kidney disease (DKD) is a devastating complication that affects an estimated third
of patients with type 1 diabetes mellitus (DM). There is no cure once the disease is …

Purpose Diabetic kidney disease (DKD) is the most common complication of type 2 diabetes
mellitus (T2DM), and its pathogenesis is not yet fully understood and lacks noninvasive and …

Introduction: Metabolomics could offer novel prognostic biomarkers and elucidate
mechanisms of diabetic kidney disease (DKD) progression. Via metabolomic analysis of …

Background Diabetic kidney disease (DKD) is the primary cause of end-stage renal disease,
raising a considerable burden worldwide. Recognizing novel biomarkers by metabolomics …

Rationale & Objective Biomarkers that provide reliable evidence of future diabetic kidney
disease (DKD) are needed to improve disease management. In a cross-sectional study, we …

Background: Diabetes is a metabolic disease and is often accompanied by severe
microvascular and macrovascular complications. A comprehensive understanding of its …

Diabetic kidney disease is the main cause of end-stage renal disease worldwide. The
prediction of the clinical course of patients with diabetic kidney disease remains difficult …

Aims Metabolomics have been used to evaluate the role of small molecules in human
disease. However, the cost and complexity of the methodology and interpretation of findings …

Here we studied plasma metabolomic profiles as determinants of progression to end-stage
renal disease (ESRD) in patients with type 2 diabetes (T2D). This nested case–control study …