Porcine reproductive and respiratory syndrome (PRRS) is an emerged disease of swine
characterized by negligible response of type I IFNs and viral persistence. We show that the …

Non-structural protein (nsp) 1 of PRRS virus is a viral antagonist for type I interferons (IFNs),
and in cells expressing nsp1, CREB-binding protein (CBP) is degraded. nsp1 is auto …

ABSTRACT Type I interferons (IFNs) IFN-α/β play an important role in innate immunity
against viral infections by inducing antiviral responses. Porcine reproductive and respiratory …

There is growing evidence that porcine reproductive and respiratory syndrome virus
(PRRSV) has developed mechanisms to subvert the host innate immune response. PRRSV …

Porcine reproductive and respiratory syndrome virus (PRRSV) infection appears to elicit a
weak innate immune response suppressing type 1 interferon (IFN) production. Recent …

Infection by porcine reproductive and respiratory syndrome virus (PRRSV) results in a weak
induction of the innate immune response. There are many genes that collectively comprise …

Porcine reproductive and respiratory syndrome virus (PRRSV) infection of swine leads to a
serious disease characterized by a delayed and defective adaptive immune response. It is …

Type I interferons (IFN-α/β) play a key role in antiviral defense, and porcine reproductive and
respiratory syndrome virus (PRRSV) is known to down-regulate the IFN response in virus …

Porcine reproductive and respiratory syndrome virus (PRRSV) is known to interfere with the
signaling of type I interferons (IFNs). Here we found PRRSV A2MC2 induced type I IFNs in …

Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus from the
Nidovirales order that causes reproductive failure and respiratory disease in pigs and poses …