Angiotensin (Ang) II, the main effector of the renin–angiotensin system (RAS), is one of the
major mediators of vascular remodeling in hypertension. Besides being a potent vasoactive …

Abstract Purpose of Review Mechanisms facilitating progression of hypertension via cross
stimulation of the renin-angiotensin system (RAS) and inflammation have been proposed …

Recent evidence shows that the renin‐angiotensin system is a crucial player in
atherosclerotic processes. The regulation of arterial blood pressure was considered from its …

Inflammation is a key mechanism in the initiation, progression, and clinical sequelae of
cardiovascular diseases (CVDs), including atherosclerosis, nephropathy, and …

Vascular inflammation is involved in the initiation and progression of atherosclerosis, and is
also present in hypertension-and diabetes-induced vascular complications. Angiotensin II …

Pathogenesis of the atherosclerotic process is deemed as multi-factorial, and characterized
by chronic inflammatory response. Although hypertension is known to be one of the most …

The RAAS through its physiological effectors plays a key role in promoting and maintaining
inflammation. Inflammation is an important mechanism in the development and progression …

More than 80% of patients with type 2 diabetes mellitus develop hypertension, and approx.
20% of patients with hypertension develop diabetes. This combination of cardiovascular risk …

The most classical view of the renin-angiotensin system (RAS) emphasizes its role as an
endocrine regulator of sodium balance and blood pressure. However, it has long become …

Inflammation, oxidative stress and hypertension are closely interrelated. Here we discuss
the (patho) physiology of vascular inflammation in hypertension, focusing specifically on the …