Efficacy and safety of tocilizumab and baricitinib among patients hospitalized for COVID-19: a systematic review and meta-analysis

J Zhang, X Fan, X Zhang, F Jiang, Y Wu… - Frontiers in …, 2023 - frontiersin.org
Introduction: Tocilizumab and baricitinib are recommended treatment options for COVID-19
patients with hyperinflammatory response; however, there is a lack of systematic review …

Efficacy and safety of baricitinib and tocilizumab in hospitalized patients with COVID-19: a comparison using systematic review and meta-analysis

JJ Cherian, M Eerike, BS Bagepally, S Das… - Frontiers in …, 2022 - frontiersin.org
Objective: This review was performed to compare the efficacy and safety among hospitalized
patients with COVID-19 who received baricitinib and those who received tocilizumab …

The effects of combination-therapy of tocilizumab and baricitinib on the management of severe COVID-19 cases: a randomized open-label clinical trial

F Dastan, H Jamaati, S Barati, S Varmazyar… - Frontiers in …, 2023 - frontiersin.org
Background: Tocilizumab and baricitinib are considered standard treatments for hospitalized
COVID-19 patients with an inflammatory status. However, the effects of co-administering …

Comparative efficacy of tocilizumab and baricitinib administration in COVID-19 treatment: a retrospective cohort study

Y Kojima, S Nakakubo, N Takei, K Kamada… - Medicina, 2022 - mdpi.com
Background and Objectives: Tocilizumab and baricitinib have been observed to improve the
outcomes of patients with coronavirus disease 2019 (COVID-19). However, a comparative …

Baricitinib versus tocilizumab for the treatment of moderate to severe COVID-19

NK Reid, KR Joyner… - Annals of …, 2023 - journals.sagepub.com
Background: To date, minimal data directly compare tocilizumab with baricitinib for treatment
in moderate to severe COVID-19. Objective: To compare the rates of in-hospital mortality …

[HTML][HTML] Tocilizumab versus baricitinib in hospitalized patients with severe COVID-19: an open label, randomized controlled trial

T Karampitsakos, O Papaioannou, P Tsiri… - Clinical Microbiology …, 2023 - Elsevier
Objective Randomized controlled trials comparing tocilizumab and baricitinib in patients with
coronavirus disease 2019 (COVID-19) are needed. This was an open-label, randomized …

Impact of the addition of baricitinib to standard of care including tocilizumab and corticosteroids on mortality and safety in severe COVID-19

M Masiá, S Padilla, JA García, J García-Abellán… - Frontiers in …, 2021 - frontiersin.org
Background: Baricitinib is a Janus kinase (JAK) inhibitor with a broader anti-inflammatory
activity than tocilizumab and an antiviral potential although no head-to-head trials are …

Outcomes and adverse effects of baricitinib versus tocilizumab in the management of severe COVID-19

JH Peterson, NS Paranjape, N Grundlingh… - Critical Care …, 2023 - journals.lww.com
Objectives: The National Institutes of Health and Infectious Diseases Society of America
guidelines recommend tocilizumab or baricitinib in the management of severe COVID-19 …

Tocilizumab for treating COVID-19: a systemic review and meta-analysis of retrospective studies

M Zhao, J Lu, Y Tang, Y Dai, J Zhou, Y Wu - European Journal of Clinical …, 2021 - Springer
Objectives COVID-19 has become a global epidemic, and effective therapies have not been
discovered up to now. We conducted this study to explore the effectiveness and safety of …

Tocilizumab vs. baricitinib in hospitalized severe COVID-19 patients: results from a real-world cohort

M Karolyi, A Gruebl, S Omid, M Saak, E Pawelka… - Infection, 2023 - Springer
Background Tocilizumab and baricitinib are recommended treatment options for
hospitalized COVID-19 patients requiring oxygen support. Literature about its efficacy and …