RAAS inhibitors are not associated with mortality in COVID-19 patients: findings from an observational multicenter study in Italy and a meta-analysis of 19 studies

A Di Castelnuovo, S Costanzo, A Antinori… - Vascular …, 2020 - Elsevier
Objective The hypothesis that been set forward that use of Renin Angiotensin Aldosterone
System (RAAS) inhibitors is associated with COVID− 19 severity. We set-up a multicenter …

Renin–angiotensin–aldosterone system inhibitors and risk of death in patients hospitalised with COVID-19: a retrospective Italian cohort study of 43,000 patients

G Trifirò, M Massari, R Da Cas, F Menniti Ippolito… - Drug Safety, 2020 - Springer
Introduction The epidemic due to severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection has been spreading globally, raising increasing concerns. There are …

Effects of renin‐angiotensin‐aldosterone system inhibitors on disease severity and mortality in patients with COVID‐19: A meta‐analysis

G Zhang, Y Wu, R Xu, X Du - Journal of medical virology, 2021 - Wiley Online Library
To investigate the effects of renin‐angiotensin‐aldosterone system (RAAS) inhibitors on the
prognosis in patients with coronavirus disease 2019 (COVID‐19). A meta‐analysis was …

[HTML][HTML] Renin-Angiotensin-Aldosterone system inhibitors in COVID-19: a review

F Ferrari, VM Martins, FD Fuchs, R Stein - Clinics, 2021 - SciELO Brasil
Among the multiple uncertainties surrounding the novel coronavirus disease (COVID-19)
pandemic, a research letter published in The Lancet implicated drugs that antagonize the …

Renin–angiotensin–aldosterone system blockers and region-specific variations in COVID-19 outcomes: findings from a systematic review and meta-analysis

U Kaur, SS Chakrabarti… - Therapeutic Advances in …, 2021 - journals.sagepub.com
Background and aims: Coronavirus disease 2019 (COVID-19) has been observed to cause
a high mortality in people with cardiometabolic diseases. Renin–angiotensin–aldosterone …

Outcomes of renin–angiotensin–aldosterone system blockers in patients with COVID-19: a systematic review and meta-analysis

A Greco, S Buccheri, P D'Arrigo… - European Heart …, 2020 - academic.oup.com
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has recently reached the pandemic level. 1 COVID-19 is …

Comparison of renin–angiotensin–aldosterone system inhibitors with other antihypertensives in association with coronavirus disease-19 clinical outcomes

YM Bezabih, A Bezabih, E Alamneh… - BMC Infectious …, 2021 - Springer
Background Reports on the effects of renin–angiotensin–aldosterone system (RAAS)
inhibitors on the clinical outcomes of coronavirus disease-19 (COVID-19) have been …

Safety and efficacy of renin–angiotensin–aldosterone system inhibitors in COVID-19 population

Y Sattar, P Mukuntharaj, M Zghouzi… - High Blood Pressure & …, 2021 - Springer
Introduction The safety of renin–angiotensin–aldosterone system inhibitors (RAASi) among
COVID-19 patients has been controversial since the onset of the pandemic. Methods Digital …

Association between renin-angiotensin-aldosterone system inhibitors and clinical outcomes in patients with COVID-19: a systematic review and meta-analysis

R Baral, V Tsampasian, M Debski, B Moran… - JAMA network …, 2021 - jamanetwork.com
Importance The chronic receipt of angiotensin-converting enzyme inhibitors (ACEIs) and
angiotensin receptor blockers (ARBs) has been assumed to exacerbate complications …

Estimation of renin-angiotensin-aldosterone-system (RAAS)-inhibitor effect on COVID-19 outcome: a meta-analysis

CJ Pirola, S Sookoian - Journal of Infection, 2020 - Elsevier
Background and rationale Some studies of hospitalized patients suggested that the risk of
death and/or severe illness due to COVID-19 is not associated with the use of angiotensin …